Carrasco CAL, Chávez BO, Flores GLE, Martínez-López M, Roldán-Valadez E

Language: Spanish
References: 12
Page: 26-31
PDF size: 507.49 Kb.

ABSTRACT

Primary bone leiomyosarcoma represents sporadic cases constituing itself a unique clinicopathological entity. It is an extremely rare bone tumor some reports have observed its location in the metaphysis of long bones. It is believed that these lesions originate from smooth muscle cells of the blood vessel wall in long bones or pluripotential mesenchymal cells. Histology is the same as the soft tissue leiomyosarcoma. The gender distribution of these tumors does not show gender differences or is lightly predominant in males. The prognosis is poor, with low survival rates. In this report, we present imaging findings and the rapid evolution in MRI and PET-CT images of a case of primary bone leiomyosarcoma.

REFERENCES

1. Sundaram M, Akduman I, White LM, McDonald DJ, Kandel R, Janney C. Primary leiomyosarcoma of bone. Am J Roentgenol 1999; 172: 771-6.

2. Petra M, Gibbons CL, Athanasou NA. Leiomyosarcoma of bone arising in association with a bone infarct. Sarcoma 2002; 6: 47-50.

3. Slavikova-Boucher L, Le Hir P, Hamze B, et al. MRI appearance of a primary leiomyosarcoma of bone with epiphyseal involvement. J Radiol 2001; 82: 927-9.

4. Miura K, Hatori M, Hosaka M, Kokubun S, Watanabe M, Ehara S. Primary leiomyosarcoma with the invasion into the intertrabecular space of bone: a case report and the review of the literatures. Clin Imaging 2001; 25: 209-14.

5. Van Laarhoven HW, Vinken M, Mus R, Flucke U, Oyen WJ, Van der Graaf WT. The diagnostic hurdle of an elderly male with bone pain: how 18F-FDG-PET led to diagnosis of a leiomyosarcoma of the adrenal gland. Anticancer Res 2009; 29: 469-72.

6. Bouaziz MC, Chaabane S, Mrad K, et al. Primary leiomyosarcoma of bone: report of 4 cases. J Comput Assist Tomogr 2005; 29: 254-9.

7. Dohi O, Hatori M, Ohtani H, Watanabe M, Kokubun S. Leiomyosarcoma of the sacral bone in a patient with a past history of resection of uterine leiomyoma. Ups J Med Sci 2003; 108: 213-20.

8. Hannachi Sassi S, Khattech R, Dhouib R, et al. Primary bone leiomyosarcoma. Anatomo-clinical, immunohistochemical, and ultrastructural study. Rev Chir Orthop Reparatrice Appar Mot 1999; 85: 865-70.

9. Wirbel RJ, Verelst S, Hanselmann R, Remberger K, Kubale R, Mutschler WE. Primary leiomyosarcoma of bone: clinicopathologic, immunohistochemical, and molecular biologic aspects. Ann Surg Oncol 1998; 5: 635-41.

10. Jelinek O, Husek K, Cerny J. Leiomyosarcoma of the bone. Act Chir Orthop Traumatol Cech 2000; 67: 49-52.

11. Mariconda M, Tacchetti C, Misiti CM, et al. Bone metastasis of leiomyosarcoma. Apropos of a case. Rev Chir Orthop Reparatrice Appar Mot 1995; 81: 338-43.

12. Myers JL, Arocho J, Bernreuter W, Dunham W, Mazur MT. Leiomyosarcoma of bone. A clinicopathologic, immunohistochemical, and ultrastructural study of five cases. Cancer 1991; 67: 1051-6.