Luis Fernando Macías VLF, Canales MM, Morales CGM

Language: Spanish
References: 14
Page: 67-72
PDF size: 206.03 Kb.

ABSTRACT

Background Measurement of nasal mucociliary clearance time with saccharine test is the gold standard for experimental models. Despite all the benefits of such test, it depends on the cooperation from the individual being tested, and rests as well on subjective elements during exploration.
Objective To determine the feasibility of use of intranasal colorant for the evaluation of nasal mucociliary clearance, and to describe a novel technique using topical fluorescein.
Participants and method An experimental analytic transversal study in which 15 healthy individuals were tested for both Anderson’s saccharine test and the measurement of mucociliary clearance time with the application of sterile sodium fluorescein and visualizing the transport towards the oropharynx with endoscopes.
Results The clearance time recorded for both test were similar (p = 0.88). The results of the saccharine test in our study group were similar to those already published.
Conclusions As far as the authors are aware, there are not studies published that compare the use of nasal colorant versus the clinical standard for nasal mucociliary clearance time. Using a visual element during the test adds objectivity and is of particular use for patients with gustatory disturbances.

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