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2012, Number 2

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Rev Hosp Jua Mex 2012; 79 (2)

Tumor del estroma gastrointestinal (GIST) como tumor anexial

Orozco-Cervantes CA, Cruz-Rubín C, García-Álvarez J, Gutiérrez-Baños JJ

Language: Spanish
References: 24
Page: 114-118
PDF size: 203.37 Kb.


ABSTRACT

The term GIST was introduced by Mazur and Clark to designate tumors gut epithelial structural features devoid of smooth muscle and immunohistochemical characteristics of Schwann cell. Represent 1% of all gastrointestinal tract tumors and are the most common mesenchymal origin with an incidence of 10-20 cases per million, between 40 and 60 years without gender predilection. Previously classified as smooth muscle tumors, schwannomas or neurofibromas, currently using immunohistochemical markers are detected as the receptor for growth factor tyrosine kinase (CD117) in 100% of cases and CD34 in 70%, and vimentin, actin, S-100 protein and desmin to distinguish them from above.


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