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Academia Mexicana de Neurología, A.C.
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2007, Number 4

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Rev Mex Neuroci 2007; 8 (4)

Cognitive impairment during the course of Idiopathic Parkinson’s Disease (IPD)

Pedroso II, Bringas VML, Salazar SS
Full text How to cite this article

Language: Spanish
References: 50
Page: 344-349
PDF size: 51.19 Kb.


Key words:

Idiopathic Parkinson’s Disease, cognitive impairment, neuropsychologic sphere.

ABSTRACT

Introduction: During the course of Idiopathic Parkinson’s Disease, there is controversy as to the presence of cognitive symptoms with a variable importance in clinical manifestations as well as their presentation in the diverse evolutive periods. Material and methods: In the investigations performed on this issue, the percentage of persons with cognitive impairment. In our study, we illustrate the alterations produced on the cognitive sphere of a group of patients by keeping in mind those parameters that are studied under the battery of tests on neuropsychologic evaluation. Results: We found that in spite of non classifying as demented according to the battery for studies that is performed at CIREN´S Clinic for Movement Disorders, 71% of patients presented alterations in the neuropsychologic sphere. We found memory, language, attention and thought as most compromised domains. Conclusion: The symptoms increase with age, with predominance of the rigidity among motor symptoms and more advanced clinical stages of the disease. Depression was present in a 50% of our patients.


REFERENCES

  1. Parrao-Díaz T, et al. Evaluación del deterioro cognitivo en una población de pacientes con enfermedad de Parkinson mediante el test minimental Parkinson. Rev de Neurol Esp 2005; 40(6): 339-44.

  2. Green J, et al. Cognitive impairments in advanced PD without dementia. Neurology 2002; 59(9): 1320-4.

  3. Fall PA, et al. Survival time, mortality, and cause of death in elderly patients with Parkinson’s disease: a 9-year followup. Mov Disord 2003; 18: 1312-16.

  4. Goetz CG, et al. Prospective longitudinal assessment of hallucinations in Parkinson’s disease. Neurology 2001; 57: 2078-82.

  5. Holroyd S, et al. Prospective study of hallucinations and delusions in Parkinson’s disease. J Neurol Neurosurg Psychiatry 2001; 70: 734-8.

  6. Chaudhuri KR. Nocturnal symptom complex in PD and its management. Neurology 2003; 61(Suppl. 3): 17-23.

  7. Aarsland D, et al. Mental symptoms in Parkinson’s disease are important contributors to caregiver distress. Int J Geriatr Psychiatry 1999; 14: 866-74.

  8. Martínez-Martín P. Calidad de vida relacionada con la salud en la enfermedad de Parkinson. Barcelona: STM Editores; 2003, p. 37-9.

  9. Scaravilli T, et al. Quality of life and sleep disorders in Parkinson’s disease. Neurol Sci 2003; 24: 201-10.

  10. Fernández HH, et al. Predictors of depressive symptoms among spouse caregivers in Parkinson’s disease. Mov Disord 2001; 16: 1123-5.

  11. Happe S, et al. The association between caregiver burden and sleep disturbances in partner of patients with Parkinson’s disease. Age Ageing 2002; 31: 349-54.

  12. Hornykiewicz O. Biochemical aspects of Parkinson’s disease. Neurology 1998; 51(Suppl. 2): S2-9.

  13. Rajput AH. Frequency and cause of Parkinson’s disease. Can J Neurol Sci 1992; 19(Suppl. 1): S103-7.

  14. Meara J, Koller WC. Parkinson’s disease and parkinsonism in the elderly.

  15. Cambridge: Cambridge University Press; 2000. Ebmeier KP, et al Dementia in idiopathic Parkinson’s disease; prevalence and relationship with symptoms and signs of Parkinsonism. Psychol Med 1991; 21: 69-76.

  16. Dubois B, et al. Cognitive deficits in Parkinson’s disease. In Boller F, Grafman J, eds. Handbook of Neuropsychol. New York: Elsevier; 1991.

  17. Mayeux R, et al. An estimate of the prevalence of dementia in idiopathic Parkinson’s disease. Arch Neurol 1988; 45: 260-2.

  18. Mayeux R, et al. A population-based investigation of Parkinson’s disease with and without dementia. Relationship to age and gender. Arch Neurol 1992; 49: 492-7.

  19. Jiménez-Roldán S, Dobato JL, Mateo D, González-Álvarez M, Novillo-Infantes MJ, Jiménez-Zuccarelli M. Depresión y enfermedad de Parkinson: bases neurobiológicas y manejo terapéutico. Neurol 1996; 11: 28-36.

  20. Perea-Bartolomé MV. Deterioro cognitivo en la enfermedad de Parkinson. Rev Neurol 2001; 12: 1182-7.

  21. Sánchez-Rodríguez JL. Déficit neuropsicológico en la enfermedad de Parkinson: relación con variables clínicas. Rev Neurol 2002; 35: 310-17.

  22. Rojo A, et al. Depression in Parkinson’s disease: clinical correlates and outcome. Parkinsonism Relat Disord 2003; 10: 23-8.

  23. Kulisevsky, et al. Trastornos cognitivos y neuropsiquiátricos en la Enfermedad de Parkinson. Barcelona: STM Editores; 2003.

  24. Adler CH. Nonmotor complications in Parkinson’s disease. Mov Disord. 2005; 20 Suppl 11: S23-9.

  25. Perea Bartolomé M. Deterioro cognitivo en la Enfermedad de Parkinson. Rev Neurol 2001; 32(12): 1182-7.

  26. Bermejo F, et al. Demencia y deterioro cognitivo en la enfermedad de Parkinson. Análisis de una serie evolutiva. Rev Clin Esp 1990; 186: 518.

  27. Ebmeier KP, et al. Dementia in idiopathic Parkinson’s disease; prevalence and relationship with symptoms and signs of Parkinsonism. Psychol Med 1991; 21: 69-76.

  28. Marttila RJ, et al. Dementia in Parkinson’s disease. Acta Neurol Scand 1976; 54: 431-41.

  29. Mayeux R, Stern Y. Intellectual dysfunction and dementia in Parkinson disease. Adv Neurol 1983; 38: 211-27.

  30. Pirozzolo FJ, et al. Dementia in Parkinson’s disease: a neuropsychological analysis. Brain Cogn 1982; 1: 71-83.

  31. Brown RG, Marsden CD. How common is dementia in Parkinson’s disease? Lancet 1984; 2: 1262-5.

  32. Golbe Ll. Youngonset Parkinson’s disease: a clinical review. Neurology. 1991; 41: 16873.

  33. Giladi N, Treves TA, Paleacu D, Shabtai H, Orlov Y, et al. Risk factors for dementia, depression and psychosis in longstanding Parkinson’s disease. J. Neural Transm. 2000; 107(1): 59-71.

  34. Herrera TJ. La depresión en el anciano. Aten Primaria. 2000 Sep 30; 26(5): 339-46

  35. Cole SA, Woodard JL, Juncos JL, Kogos JL, Youngstrom EA, et al. Depression and disability in Parkinson’s disease. J Neuropsych Clin Neurosci. 1996 Winter; 8(1): 20-5.

  36. Parkinson J. An essay on the shaking palsy. London: Sherwood, Nelly & Jones; 1817.

  37. Charcot JM, Vulpian A. De la paralysie agitante. Gazette Hebdomadaire de Médecine et de Chirurgie 1861; 8: 7657.

  38. Charcot JM. Leçons sur les maladies du système nerveux. 2ed. Paris: Delahaye et Lecrosnier; 1875.

  39. Ostrosky-Solis F. Características neuropsicológicas en la enfermedad de Parkinson. Rev Neurol 2000; 30: 782-96.

  40. Knopman D, Boeve B, Petersen R. Essentials of the proper diagnoses of mild cognitive impairment, dementia and major subtypes of dementia. Mayo Clinic Proc 2003; 78: 1290-308.

  41. Hughes AJ. Accuracy of clinical diagnosis of idiopathic Parkinson’s disease: a clinico pathological study of 100 cases. J Neurol Neurosurg Psychiatry 1992; 55: 181-4.

  42. Matthews CG, Haaland KY. The effects to symptom duration on cognitive and motor performance in parkinsonism. Neurol 1979; 29: 9516.

  43. Growdon JH, Corkin S. Cognitive impairments in Parkinson’s disease. Adv Neurol 1987; 45: 383-92.

  44. Caparros D, et al. H. Which factors predict cognitive decline in Parkinson’s disease? J Neurol Neurosurg Psychiatry 1994; 57: 1203-7.

  45. Vingerhoets G et al. Predictors of cognitive impairment in advanced Parkinson’s disease. J Neurol Neurosurg Psychiatry 2003; 74: 793-6.

  46. Burn DJ. Beyond the iron mask: towards better recognition and treatment of depression associated with Parkinson’s disease. Mov Disord 2002; 17: 445-54.

  47. Zesiewicz TA, Hauser RA. Depression in Parkinson’s disease. Curr Psychiatr Rep 2002; 4: 69-73.

  48. Mossner R, Henneberg A, Schmitt A, et al. Allelic variation of serotonin transporter expression is associated with depression in Parkinson’s disease. Mol Psychiatry 2001; 6: 350-2.

  49. Fall PA, Saleh A, Fredrickson M, Olsson JE, Granerus AK. Survival time, mortality, and cause of death in elderly patients with Parkinson’s disease: a 9-year follow-up. Mov Disord 2003; 18: 1312-16.

  50. Martínez-Martín P, Guerrero-Díaz MT, Frades-Payo B. Alteraciones Neuropsicológicas en la enfermedad de Parkinson: Evaluación e impacto sobre el cuidador. Rev Neurol 2004; 39: 639-45.




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Rev Mex Neuroci. 2007;8