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2013, Number 4

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Acta Pediatr Mex 2013; 34 (4)

Burst-suppression pattern in the electroencephalogram of newborns and infants. Its clinical expression

Cervantes-Blanco JM, Ruiz–García M, García–Briseño A, Hernández–Antúnez BG, Díaz–García L

Language: Spanish
References: 19
Page: 180-188
PDF size: 756.08 Kb.


ABSTRACT

Burst-suppression pattern in the electroencephalogram (EEG) is associated with severe brain damage and has a bad prognosis in 85% of the cases.
Objectives. To identify the prevalence of the EEG burst-suppression pattern (BSP) in fullterm newborns and infants, determine its etiology, clinical features and course.
Methods. A retrospective study was conducted. Between January 2008 and December 2012, 4,891 EEGs were reviewed. The EEGs of newborns and infants (‹ 3 months of age) with BSP were selected.
Results. 11 cases identified with burst suppression pattern. The overall prevalence of which was 3.5%; 8.1% among the newborns and 1.2% among infants. Seizures were the main reason for doing an EEG in the newborn period in 7 patients and after day 28 in three. The clinical manifestations were abnormal level of consciousness (n=8), hypotonia (n=2), and spasticity (n=6). The main causes were hypoxic ischemic injury, stroke and kernicterus. There were two cases of early infantile epileptic encephalopathy. Two patients died before the third month of age; 8 survived an average of 13 months. All had epilepsy, neurologic retardation and disability. Two patients had persistent EEG burst-suppression pattern; 1 and 3 months after the neonatal period respectively; 7 had focal spikes and an asymmetric pattern.
Conclusions. Electroencephalographic burst-suppression pattern predicts a severe neurologic injury in fullterm newborns and infants.


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