Barriga AF, López VJL, Trejo SOA, Tamariz HE, de la Torre RF, Mendoza LLD, Amador PC

Language: Spanish
References: 11
Page:
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ABSTRACT

Background: Vaginal intraepithelial neoplasia (VAIN) is the 1-4% of all gynecological malignancies associated with human papillomavirus high risk in 74.3%.
Objective: To determine the prevalence of infection with human papillomavirus high-risk patients with vaginal intraepithelial neoplasia by molecular evidence (chain reaction polymerase PCR).
Material and Methods: We performed a prospective cross-sectional study in patients with histologically confirmed vaginal intraepithelial neoplasia colposcopy service Regional Hospital Adolfo Lopez Mateos, ISSSTE. Sought in each major risk factors, were sampled cervical brush and colposcopy was performed. The final data were analyzed and plotted using SPSS version 20.
Results: The cumulative incidence of vaginal intraepithelial neoplasia was 0.32% with a prevalence of 31.6%. The promised age was 50.31 ± 11 years, of which 22 (56.41%) had VAIN 1, 14 (35.89%) VAIN 2 and 3 (7.69%) VAIN 3. The lesions were found in 16 (41.0%) in the upper 1/3 of the vagina, in 1 (2.6%) in the 1/3 through the vagina, in 1 (2.6%) in the lower 1/3 of the vagina in 13 (33.33%) in the dome and in 8 (20.51%) multifocal. The high-risk HPV was positive in 69.23% being HPV 16 detected in 8 (20.51%), 18 to 2 (5.12%), 16 and 18 in 1 (2.56%) and the pool to 12 in 16 (41.02%).
Conclusions: Vaginal intraepithelial neoplasia is a lesion with an incidence of 0.32% which is associated with human papillomavirus high risk and to cancer in 69.23%.

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