Hernández-Navarrete LS, Hernández-Jiménez JD, Jiménez-López LA, Budar-Fernández LF, Méndez-López MT, Martínez-Mier G

Language: Spanish
References: 8
Page: 450-453
PDF size: 360.77 Kb.

ABSTRACT

Background: Jehovah’s Witness refuse blood transfusion, but they accept organ transplantation, albumin, immunoglobulin, vaccines and clotting factors.
Clinical cases: We present 3 kidney transplants in Jehovah’s Witness patients (two male and one female) without blood transfusion, with a mean age of 31.33 years and a mean body mass index of 20.99 kg/m2. All patients underwent pre transplant peritoneal dialysis for an average of 52.3 months. Two transplants came from living donors and one from deceased donor with a cold ischemia of 23 hours. The donors were two females and one male, with a mean age of 34.33 years. All patients received pre transplant erythropoietin and iron dextran and an intraoperative cell saver were used. Hemoglobin, hematocrit, red blood cells and serum creatinine levels, as well as the glomerular filtration at 24 months postransplant were stable. All patients received induction with basiliximab and initial immunosuppression with calcineurin inhibitors. One of the patients had a peri renal hematoma as a complication, which required a surgery 20 days post-transplant. At 5, 26 and 36 months postransplant the three patients are alive and with functional graft.
Conclusion: It is possible to perform kidney transplantation without transfusion in Jehovah’s Witness, obtaining an acceptable global survival without acute rejection.

REFERENCES

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