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ISSN 1561-3194 (Electronic)

2012, Number 3

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Rev Ciencias Médicas 2012; 16 (3)

Waardenburg's syndrome: clinical classification of a family

Castro PF, Sanabria NJG, Menéndez GR

Language: Spanish
References: 14
Page: 161-171
PDF size: 315.07 Kb.


ABSTRACT

Background: Although sensorineural hearing loss and iris pigmentary changes have been described, the association betwe en these two elements has not been previously studied.
Objectives: to describe and analyze the possible association of hypoacusis and the intensity of this with the color of the iris in a family suffering from this syndrome; which will constitute a new co ntribution to the understanding of Waardenburg Syndrome (WS).
Material and Method: an observational, cross -sectional and descriptive case - study was carried out having some analytic aspects in people suffering from WS in Sandino municipality, Pinar del Rio . Measures of review to conduct qualitative variables and chi square test X2 to measure the association of 95% of confidence.
Results: about 15 individuals presented sensorineural hearing loss of different distribution and intensity, prevailing brown and b lue bilateral eyes. A greater frequency of individuals with hypoacusis and blue eyes was found in association between the two variables (X2= 6,47, gl = 1; p = 0.01). Hypoacusis was greater in blue-eyed individuals (85.7% with severe or profound hypoacusis) , three times superior than in the other color of eyes.
Conclusions: an association between the blue color of the iris and the presence of hypoacusis along with a greater intensity of hearing loss in individuals suffering from WS was observed.


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