Martínez-Mier G, Castillo-Chiquete RA, Alvarado-Arenas RA, Budar-Fernández LF, Méndez-López MT, Ávila-Pardo SF, Calzada-GrijalvaII JF

Language: Spanish
References: 20
Page: 93-96
PDF size: 201.72 Kb.

ABSTRACT

Introduction: Renal transplantation is the most effective procedure to treat patients with chronic renal failure; however, the immunosuppressive regimen used, including rejection therapies, is associated with numerous gastrointestinal surgical complications. Material and methods: Retrospective chart review of patients who underwent gastrointestinal surgery post-transplantation during a 10-year period. Age, sex, donor type, immunosuppression, time of occurrence after transplantation, diagnosis, surgery, postoperative course and survival were examined. Results: From 500 kidney transplants, 20 (4%) had a gastrointestinal surgical complication. Mean age of these patients was 39 years; 5 of them (25%) had a deceased donor. 65% patients had basiliximab induction and the most common immunosuppression was cyclosporine-mycophenolate mofetil-prednisone, in 13 patients. Mean post-transplantation time for complications was 20 months. The most common type of surgical disease was colonic, in 11 patients, and nine patients underwent emergency surgery. Postoperative mortality was 35% (7 patients). The most common postsurgical immunosuppression prescription was not to change the dosage, in 55% (11 patients). One year graft survival of patients who did not die perioperatively was 90%. Conclusion: Gastrointestinal surgical complications in kidney transplant patients are rare, but have a high mortality incidence. Colonic pathology was the most common complication, and it should be managed expeditiously.

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