Sandoval-Cabrera DV, Valenzuela-Plata A, Izaguirre-Gutiérrez VF, Domínguez-Borgúa A

Language: Spanish
References: 17
Page: 639-645
PDF size: 683.28 Kb.

ABSTRACT

Scleromyositis is considered an overlap-syndrome, involving clinical and immunological characteristics of systemic sclerosis and polymyositis/dermatomyositis. We present the case of a 69-year-old male, who was admitted to our service by complaining proximal muscular weakness, the approach and review of literature. It is not common at this age; the most common cause is a neoplastic cause, which was discarded in the patient, making it of interest. Also that overlap of immunological diseases is rare.

REFERENCES

1. Jablonska S, Blaszcyk M. Scleromyositis: A scleroderma/ polymyositis overlap syndrome. Clin Rheumatol 1998;17:465-467.

2. Törok L, et al. PM-SCL autoantibody positive scleroderma with polymyositis. JEADV 2004;18:356-359.

3. Jury EC, D’ Cruz D, Morrow WJ. Autoantibodies and overlap syndromes in autoimmune rheumatic disease. J Clin Pathol 2001;54:340-347.

4. Fernández Serna M. Dropped Head syndrome in a patient with scleromyositis. Clin Rheumatol 2013;19:32-34.

5. Fernández, et al. Immunopathologic classification of myositis. Medicine 2013;92.

6. Ho T, Reveille J. The clinical relevance of autoantibodies in scleroderma. Arthritis Research & Therapy 2003;5:80-93.

7. Darwich E, Herrero C. Utilidad clínica de los anticuerpos en las enfermedades autoinmunes del tejido conectivo. Med Cutan Iber Lat Am 2010;38:143-151.

8. Balbir A, Braun Y. Scleroderma overlap syndrome. IMAJ 2011;13:14-20.

9. Hanke, et al. Antibodies against PM/Scl-75 and PM/ Scl-100 are independent markers for different subsets of systemic sclerosis patients. Arthritis Research & Therapy 2009;11:1-9.

10. Koschik, et al. Anti-PM-SCL antibody in patients with systemic sclerosis. Clin Exp Rheumatol 2012;30:12-16.

11. Brouwer R, et al. The human exosome: an autoantigenic complex of exoribonucleases in myositis and scleroderma. Arthritis Res 2001;3:102-106.

12. Raijmaker R, et al. PM–Scl-75 is the main autoantigen in patients with the polymyositis/scleroderma overlap syndrome. Arthirtis & Rheumatism 2004;50:565-569.

13. Ioannou Y, et al. Myositis overlap syndromes. Current Opinion in Rheumatology 1999;11:468-474.

14. Jablonska S, Blaszyk M. Scleromyositis (scleroderma/ polimyositis overlap) isanentity JEADV 2004;18:265-266.

15. Janet E. Scleroderma overlap syndromes. Opin Rheumatol 2002;14:704-710.

16. Restrepo J. Dermatomiositis-polimiositis. Revista Colombiana de Reumatología 2003;10:135-141.

17. Zakrzewska-Pniewska B, et al. Sympathetic skin response in scleroderma, scleroderma overlap syndromes and inflammatory. Myopathies Clin Rheumatol 1999;18:473- 480.