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2012, Number 4

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Rev Latinoam Psiquiatría 2012; 11 (4)

Estudios de neuroimagen estructural en pacientes con diagnóstico de esquizofrenia

Ramírez-Bermúdez J, Valadez J, León-Ortiz P, de la Fuente-Sandoval C
Full text How to cite this article

Language: Spanish
References: 11
Page: 164-167
PDF size: 435.39 Kb.


Key words:

Magnetic resonance imaging, Diffusion tensor imaging, Voxel-based morphometry, Schizophrenia.

ABSTRACT

Structural brain imaging techniques represent a valuable source of information regarding de nervous system abnormalities in subjects with a schizophrenia diagnosis. Magnetic resonance imaging voxel-based morphometry allows us to explore the grey matter brain regions with volumetric deficits. By means of this technique it is possible to conclude that the most consistent deficits have been found, at least, in the following structures: left medial temporal lobe, left superior temporal gyrus, left medial frontal gyrus, left parahipocampal gyrus, right superior temporal gyrus. In a complementary form, Magnetic Resonancia Diffusion Tensor Imaging provides a source to explore abnormalities in white matter structural connectivity. By means of this technique, in may be established that the most consistent abnormalities in white matter connections include, at least, the following: uncinated fasciculus, cingulum, and arcuate fasciculus. Structural brain imaging support the hypothesis of robust abnormalities in the brain architecture of subjects with a schizophrenia diagnosis.


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Rev Latinoam Psiquiatría. 2012;11