Canciano CE, Figueroa ME, Acevedo GL, León LE

Language: Spanish
References: 16
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ABSTRACT

Introduction: obesity in children continues to ascend relating it to the appearance of atherosclerotic lesions in obese young adults.
Objective: to identify prognostic variables associated with obesity in adolescents belonging to 5 neighboring polyclinics of San Antonio de los Baños, Artemisa province.
Methods: a multicenter prospective cohort study was conducted in the period from January 2006 until May 2012 on 5 neighboring clinics and San Antonio de los Baños municipality, Artemisa province to determine prognostic variables associated with obesity as independent variable during adolescence. It was analyzed: clinical and demographic variables found, complementary laboratory exams utility, referred pathological family antecedents. It was calculated a sample for a relative risk of 23.1, 95% confidence and accuracy of 96%, randomly selected and matched by age and sex into 2 groups of 150 patients: group A (obese) and group B (not obese).
Results: central fat distribution (RR 3.3) and prehypertension (RR 3.1) were associated with obesity, with predominance of men 1.5 / 1. hypertriglyceridemia (global mean 4.8 mmol/L DE ± 2.8) and steatohepatitis (23.3 %), positive complementary laboratory exams were more frequent in the obese, although the positive microproteinuria had wide sensitivity (0.83) and specificity (0.79). Obesity (23.3 %) and arterial hypertension (22.6 %), personal antecedents had a higher incidence in group A. The morbidity analysis indicated central obesity (coefficient 5.432) and microproteinuria as prognostic variables of greater interaction.
Conclusions: prehypertension, visceral fat distribution and poor metabolic control constitute bad prognostic factors in obese adolescent whose vascular endothelium is early injured influenced by the genetic load.

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