2014, Number 1
Rev Hematol Mex 2014; 15 (1)
Nolasco-De la Rosa AL, Mosiñoz-Montes R, Román-Guzmán E, Hernández-Quintero JM, Reyes-Miranda AL, Quero-Sandova Fl
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ABSTRACTCastleman’s disease, described in 1954, is a linfoproliferative, benign, low-frequent disorder. There are two histologic kinds of this disorder: hialinovascular type (90%) and plasmatic cell type, the latter can be associated to fever, weight loss, dermic eruption, anemia and hipergammaglobulinemia; the most common affected places are thorax, stomach and neck; it can also develop (but less frequently) on pelvis and pancreas. Its etiopathology is confusing and includes the interleukine 6 expression and the probable association with the 8-type human herpes virus. The only curative treatment is the surgical excision. This paper reports the case of a 55-year-old male patient with hyalinovascular Castleman’s disease and thoracic localization.