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2014, Number 1

Rev Hematol Mex 2014; 15 (1)

Castleman’s Disease

Nolasco-De la Rosa AL, Mosiñoz-Montes R, Román-Guzmán E, Hernández-Quintero JM, Reyes-Miranda AL, Quero-Sandova Fl
Full text How to cite this article

Language: Spanish
References: 8
Page: 21-25
PDF size: 305.37 Kb.


Key words:

Castleman disease, human herpes virus 8, hyalinovascular, plasma cell-like.

ABSTRACT

Castleman’s disease, described in 1954, is a linfoproliferative, benign, low-frequent disorder. There are two histologic kinds of this disorder: hialinovascular type (90%) and plasmatic cell type, the latter can be associated to fever, weight loss, dermic eruption, anemia and hipergammaglobulinemia; the most common affected places are thorax, stomach and neck; it can also develop (but less frequently) on pelvis and pancreas. Its etiopathology is confusing and includes the interleukine 6 expression and the probable association with the 8-type human herpes virus. The only curative treatment is the surgical excision. This paper reports the case of a 55-year-old male patient with hyalinovascular Castleman’s disease and thoracic localization.


REFERENCES

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  3. O’ReillyPE Jr, Joshi VV, Holbrook CT, Weisenburger DD, et al. Multicentric Castleman’s disease in a child with prominent thymic involvement: A case report and brief review of the literature. Mod Pathol 1993;6:776-780.

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  8. Sobrevilla CP, Aviles SA, Cortés PD, Rivas VS. Características clínicopatológicas de la enfermedad de Castleman. Experiencia en el Instituto Nacional de Cancerología. Cir Ciruj 2009;77:187-192.




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CÓMO CITAR (Vancouver)

Rev Hematol Mex. 2014;15