2014, Number 1
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Rev Esp Med Quir 2014; 19 (1)
Aminophylline as inducer of lung maturity in patients with diabetes mellitus types 1 and 2, and gestational diabetes; perinatal outcome
Serrano BMÁ, Serrano BJR
Language: Spanish
References: 16
Page: 30-38
PDF size: 438.28 Kb.
ABSTRACT
Background: During pregnancy there are frequent changes in the metabolism
of carbohydrates and 1 to 3% of all pregnant women have
impaired glucose tolerance or develop gestational diabetes mellitus.
Objectives: To evaluate the usefulness of aminophylline to induce lung
maturity in pregnant patients with gestational or pre-gestational diabetes
as well as analysis of perinatal outcomes.
Material and method: We performed a retrospective review of 1,500
cases of maternal-fetal medicine service of the Regional Hospital Adolfo
López Mateos of January 1, 2007 to December 31, 2011, including
pregnant patients diagnosed with gestational or pregestational diabetes,
who initiated prenatal care later than the beginning of the third trimester
of pregnancy, with no previous management for fetal lung maturation.
Results: No statistically significant differences between the different
study groups regarding the type of diabetes, age distribution, hypertensive
disease associated weights Capurro products and valuation.
Conclusions: Aminophylline is an effective alternative for the prevention
of respiratory distress syndrome in patients with preexisting diabetes
or gestational properly induce lung maturity, not being necessary to
administer more than 2 patterns the same.
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