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2005, Number 3

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Rev Med Inst Mex Seguro Soc 2005; 43 (3)

Non-Neoplastic Enlargement of Salivary Glands: Clinico-Histologic Analysis

González GMB, Torres TMA, Martínez MG
Full text How to cite this article

Language: Spanish
References: 100
Page: 189-197
PDF size: 155.82 Kb.


Key words:

mucous extravasation cyst, chronic sclerosing chronic sclerosing, Sjögren’s syndrome, mucous retention cyst.

ABSTRACT

We carried out a retrospective study on nonneoplastic enlargement of the salivary glands at the Oral Histopathology Diagnostic Center of the Autonomous Metropolitan University at Xochimilco (UAM-Xochimilco) in Mexico during a period of 24 years (1979–2003). From 5,625 biopsies received and analyzed, a total of 461 (8.2%) were nonneoplastic enlargement of the salivary glands; for each case, we registered demographic data as well as clinic characteristics. These lesions were characterized as a heterogeneous group of pathologic entities among which we included local, obstructive, infectious, and immunopathologic lesions. The most frequent lesion was the extravasation cyst in 341 (74%) cases, followed by chronic sialoadenitis and Sjögren’s syndrome with 54 (11.7 %) and 41 (8.8 %) cases, respectively, and at a lesser percentage mucous retention cyst, sialosis, benign lymphoepithelial lesions and those related with sialolytes. Females were affected more frequently; mean age was second to third life decades. These lesions were most frequently localized on inferior labial mucosa.


REFERENCES

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  44. organizer regions (NORs) evaluation of lingual salivary

  45. glands of chronic alcoholics. J Oral Pathol Med 2002;

  46. 31:585-589.

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  58. ocular and oral involvement in Sjögren’s syndrome.

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  61. of labial salivary gland inflammation with keratoconjunctivitis

  62. sicca. Analysis of 618 patients with

  63. suspected Sjögren’s syndrome. Arthritis Rheum

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  66. features, immunopathogenesis, and management.

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  69. syndrome. Assessment as a diagnostic criterion in 362

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  72. Sjogren’ syndrome. Proposed criteria for classification.

  73. Arthritis Rheum 1986;29:577-585.

  74. Figura 9. Lóbulos de glándulas salivales

  75. mucosecretoras con focos de infiltrado linfocítico

  76. y marcada sialectasia

  77. Batzakis JG. Tumours of the head and neck. Clinical and pathological considerations. Second edition. New York: Williams and Wilkins; 1984. p. 100-120.

  78. Scully C. An update on recent advances in the understanding of non-neoplasic diseases of the salivary glands. Br J Oral Maxillofac Surg 1992;30:244-247.

  79. Ellis GL, Auclair PL. Tumours of the salivary glands. Maryland: Armed Forces Institute of Pathology; 1996. p. 411-425.

  80. Cataldo E, Masadoni A. Mucoceles of the oral mucous membrane. Arch Otolaryngol 1970;91:360-365.

  81. Yamasoba T, Tayama N, Syoji M, Fukuta M. Clinicstatistical study of lower lip mucoceles. Head Neck 1990;12:316-320.

  82. Shear M. Cysts of the salivary glands: mucous extravasation cysts: mucous retention cysts, ranula. En: Cyst of the oral regions. Third edition. United Kingdom: Oxford; 1992. p. 212-222.

  83. Neville BW, Damm DD, Allen CM, Bouquot JE. Oral and maxillofacial pathology. Second edition. USA: WB Saunders Company; 2002. p. 389-404.

  84. Harrison JD. Salivary mucoceles. Oral Surg Oral Med Oral Pathol 1975;39:268-278.

  85. Bagan JVS, Silvestre DFJ, Penarrocha DM, Milian MMA. Clinic-pathological study of oral mucoceles. Av Odontoestomatol 1990;6:394-395.

  86. Blitzer A. Inflammatory and obstructive disorders of salivary glands. J Dent Res 1987;66(Spec Iss):675-679.

  87. Williams HK, Connor R, Edmondson H. Chronic sclerosing sialadenitis of the submandibular and parotid glands. A report of a case and review of the literature. Oral Surg Oral Med Oral Pathol Oral Radiol Endod 2000;89:720-723.

  88. Sierra Y, Sulbarán J, González JEA. Patología de glándulas salivales: Correlación clínico-morfológica en 140 biopsias. Patologia 1986;24:109-128.

  89. Mandel L, Surattanont F. Bilateral parotid swelling: a review. Oral Surg Oral Med Oral Pathol Oral Radiol Endod 2002;93:221-237.

  90. Carda C, Gómez de Ferraris ME, Arriaga A, Carranza M, Peydró A. Sialosis parotídea alcohólica: estudio estructural y ultraestructural. Med Oral 2004;9:24-32.

  91. Severgnini M, Ferraris ME, Carranza M. Nucleolar organizer regions (NORs) evaluation of lingual salivary glands of chronic alcoholics. J Oral Pathol Med 2002; 31:585-589.

  92. Jonsson R, Moen K, Vestrheim D, Szodoray P. Current issues in Sjögren’ syndrome. Oral Dis 2002;8:130-140.

  93. Sapiro MS, Eisenberg E. Sjögren’ syndrome (sicca complex). Oral Surg Oral Med Oral Pathol 1978;45: 591- 599.

  94. Bell M, Askari A, Bookman A, Frydrych S, Lamont J, McComb J, et al. Sjögren’s syndrome: a critical review of clinical management. J Rheumatol 1999; 26:2051-2061.

  95. Vitali C, Haralampos M. The European community study group on diagnostic criteria for Sjögren’s syndrome. Sensitivity and specificity of tests for ocular and oral involvement in Sjögren’s syndrome. Ann Rheum Dis 1994;53:637-647.

  96. Daniels TE, Whitcher JP. Association of patterns of labial salivary gland inflammation with keratoconjunctivitis sicca. Analysis of 618 patients with suspected Sjögren’s syndrome. Arthritis Rheum 1994;37:869-877.

  97. Scully C. Sjögren’s syndrome: clinical and laboratory features, immunopathogenesis, and management. Oral Surg Oral Med Oral Patthol 1986;62:510-523.

  98. Daniels TE. Labial salivary gland biopsy in Sjögren’s syndrome. Assessment as a diagnostic criterion in 362 suspected cases. Arthritis Rheum 1984;27:147-156.

  99. Fox RI, Robinson CA, Curd JG, Kozin F, Howell V. Sjogren’ syndrome. Proposed criteria for classification. Arthritis Rheum 1986;29:577-585.




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Rev Med Inst Mex Seguro Soc. 2005;43