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2014, Number 1

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Rev Mex Cardiol 2014; 25 (1)

Behavior of hospital fatality in patients with acute myocardial infarction with the use of reperfusion therapy in 12 years of work in the Intensive Coronary Unit of the Institute of Cardiology at Havana, Cuba

Rodríguez-Londres J, Quirós-Luis JJ, Castañeda-Rodríguez G, Hernández-Veliz D, Valdés-Rucabado JA, Nadal-Tur B, Rodríguez-Nande L

Language: Spanish
References: 28
Page: 7-14
PDF size: 188.85 Kb.


ABSTRACT

Introduction: The cardiovascular diseases are the first cause of mortality in the world. The reperfusion therapy of acute myocardial infarction has considerably diminished the mortality for that cause. Objectives: To evaluate the behavior of the reperfusion therapy in this entity and their influence of the hospital lethality. Method: An observational, retrospective and descriptive study was carried in 2,493 patients admitted in the Intensive Coronary Cares Unit in the Institute of Cardiology and Cardiovascular Surgery, with the diagnosis of acute myocardial infarction during the period between January of the 2001 and December of the 2012. The patients were characterized according to clinical variables and it was calculated the general hospital lethality and the related with the different reperfusion methods. Results and discussion: There was an increase in the number of patients admitted with acute myocardial infarction. The general lethality average was of 7.1%. The lethality in patients that received the primary, rescue and in shock percutaneous coronary interventionism was of 4.1%, 10.8% and 34.6%, respectively. Since 2001 the number of patients treated by percutaneous coronary interventionism has increased, while the application of the fibrinolysis was less used at the end of the study than before. The lethality of these therapeutic options was of 4.1% against 5%, respectively, this results being less when compared to those patients that didn’t receive this treatment (13%). Conclusions: The appropriate application of the reperfusion methods has demonstrated favorable influence in acute myocardial infarction lethality in the hospital.


REFERENCES

  1. Steg G, James S, Atar D et al. Guía de práctica clínica de la ESC para el manejo del infarto agudo de miocardio en pacientes con elevación del segmento ST. Rev Esp Cardiol. 2013; 66 (1): 1-46.

  2. Ministerio de Salud Pública. Dirección nacional de registros médicos y estadísticas de salud. Anuario estadístico de salud 2011. Ministerio de Salud Pública; 2011 [acceso 4 de noviembre de 2013]. Disponible en: http: //www.sld.cu/servicios/estadisticas.

  3. Ministerio de Salud Pública. Dirección nacional de registros médicos y estadísticas de salud. Anuario estadístico de salud 2012. Ministerio de Salud Pública; 2012 [acceso 4 de noviembre de 2013]. Disponible en: http: //www.sld.cu/servicios/estadisticas.

  4. Van’t Hof AWJ. Reperfusión satisfactoria: del rescate epicárdico al miocárdico. Rev Esp Cardiol. 2010; 63 (7): 757-759.

  5. Mele AEF. Avances en la reperfusión del infarto agudo de miocardio. Realidad en Latinoamérica. Rev Esp Cardiol. 2010; 63 (2): 12-19.

  6. McManus DD, Gore J, Yarzebski J et al. Recent trends in the incidence, treatment, and outcomes of patients with STEMI and NSTEMI. Am J Med. 2011; 124: 40-47.

  7. Herzberg T, Johansson P, Held C et al. Association between adoption of evidence-based treatment and survival for patients with ST-elevation myocardial infarction. J Am Med Assoc. 2011; 305: 1677-1684.

  8. Fox KA, Caruthers KF, Dunbar DR et al. Underestimated and under recognized: the late consequences of acute coronary syndrome (GRACE UK- Belgian Study). Eur Heart J. 2010; 31: 2755-2764.

  9. Antman E. Infarto del miocardio con elevación del ST: tratamiento. En: Zipes DP, Libby P, Bonow R, Braunwald E, editores. Tratado de cardiología. 7a. ed. Madrid: Elsevier; 2007. pp. 1167-1180.

  10. Puymirat E, Simon T, Steg PG et al. Association of changes in clinical characteristics and management with improvement in survival among patients with ST-elevation myocardial infarction. JAMA. 2012; 308: 998-1006.

  11. Conroy RM, Pyorala K, Fitzgerald AP, Sans S, Menotti A, De Backer G et al. Estimation of ten-year risk of fatal cardiovascular disease in Europe: the SCORE project. Eur Heart J. 2003; 24: 987-1003.

  12. Perk J, Backera G, Gohlkea H et al. Guía europea sobre prevención de la enfermedad cardiovascular en la práctica clínica (versión 2012). Rev Esp Cardiol. 2012; 65 (10): 937.e1-e66

  13. Yeh RW, Sidney S, Chandra M et al. Population trends in the incidence and outcomes of acute myocardial infarction. N Engl J Med. 2010; 362: 2155-2165.

  14. Gibson RS. Non-Q wave myocardial infarction: prognosis, changing incidence and management. In: Gersh BJ, Rahimtoola SH, editors. Acute myocardial infarction. New York: Chapman & Hall; 1997. pp. 403-433.

  15. Fox KA, Dabbous OH, Goldberg RJ et al. Prediction of risk of death and myocardial infarction in the six months after presentation with acute coronary syndrome: prospective multinational observational study (GRACE). Br Med J. 2006; 333: 1091.

  16. Aros F, Heras M, Vila J et al. Reducción de la mortalidad precoz y a 6 meses en pacientes con IAM en el periodo 1995-2005. Datos de los registros PRIAMHO I, II y MASCARA. Rev Esp Cardiol. 2011; 64: 972-980.

  17. Ting HH, Rihal CS, Gersh BJ. Regional systems of care to optimize timeliness of reperfusion therapy for ST-elevation myocardial infarction: the Mayo Clinic STEMI protocol. Circulation. 2007; 116: 729-736.

  18. Mandelzweig L, Battler A, Boyko V et al. The second Euro Heart Survey on acute coronary syndromes: characteristics, treatment, and outcome of patients with ACS in Europe and the Mediterranean Basin in 2004. Eur Heart J. 2006; 27: 2285-2293.

  19. Widimsky P, Wijns W, Fajadet J et al. Reperfusion therapy for ST elevation acute myocardial infarction in Europe: description of the current situation in 30 countries. Eur Heart J. 2010; 31: 943-957.

  20. Díaz D. Angioplastia primaria frente a angioplastia precoz tras la fibrinólisis en el infarto agudo de miocardio con ST elevado: GRACIA-2. Rev Elec de Medicina Int [Internet] 2008. [acceso 3 de julio de 2008]; 8 (6): [3 p.]. Disponible en: http: //remi.uninet.edu.

  21. Ellis SG, Da Silva ER, Hendricks G. Randomized comparison of rescue angioplasty with conservative management of patients with early failure of thrombolysis for acute myocardial infarction. Circulation. 1994; 90: 2280-2284.

  22. Goldberg RJ, Spencer FA, Gore JM et al. Thirty-year trends (1975 to 2005) in the magnitude of, management of, and hospital death rates associated with cardiogenic shock in patients with acute myocardial infarction: a population-based perspective. Circulation. 2009; 119: 1211-1219.

  23. Hochman JS. Early revascularization in acute myocardial infarction complicate by cardiogenic shock. SHOCK investigators. Should we emergently revascularization occluded coronaries for cardiogenic shock? N Engl J Med. 1999; 341: 625-634.

  24. Rogers WJ, Canto JG, Lambrew CT et al. Temporal trends in the treatment of over 1.5 million patients with myocardial infarction in the U.S. from 1990 through 1999: the National Registry of Myocardial Infarction 1, 2 and 3. J Am Coll Cardiol. 2000; 36: 2056-2063.

  25. Andrés E, Cordero A, Magán P et al. Mortalidad a largo plazo y reingreso hospitalario tras infarto agudo de miocardio: un estudio de seguimiento de ocho años. Rev Esp Cardiol. 2012; 65: 414-420.

  26. McManus DD, Gore J, Yarzebski J et al. Recent trends in the incidence, treatment, and outcomes of patients with STEMI and NSTEMI. Am J Med. 2011; 124: 40-47.

  27. Roger VL, Go AS, Lloyd-Jones DM et al. Executive summary: heart disease and stroke statistics-2012 update: a report from the American Heart Association. Circulation. 2012; 125: 188-197.

  28. Fox KA, Carruthers KF, Dunbar DR et al. Underestimated and under recognized: the late consequences of acute coronary syndrome (GRACE UK-Belgian Study). Eur Heart J. 2010; 31: 2755-2764.




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