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Revista Mexicana de Neurociencia

Academia Mexicana de Neurología, A.C.
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2014, Number 5

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Rev Mex Neuroci 2014; 15 (5)

Neuropsychological profile of major neurocognitive impairment due to Alzheimer’s disease, vascular and frontotemporal disorders in a Mexican population

Castillo-Rubén A, De Luna-Castruita JÁ, López-García R, Pliego-Flores FM, Sánchez-Rubio U, Gallegos EG
Full text How to cite this article

Language: Spanish
References: 26
Page: 259-266
PDF size: 161.89 Kb.


Key words:

Alzheimer disease, frontotemporal disorder, mayor neurocognitive disorder, vascular disease.

ABSTRACT

Introduction: The most important aspects of dementia in its final stages are dependency and severe cognitive impairment.
Objetive: To carry out a comparative study of three different types of neurocognitive disorder: Alzheimer’s disease, frontotemporal disorder, and vascular disease to identify the neuropsychological profiles in advanced stages.
Methods: We retrospectively analyzed neuropsychological data of 86 patients diagnosed with dementia who were assessed between January 2002 and July 2012. Cognitive processes were evaluated in each patient using the Wechsler memory scale and Wechsler Adult Intelligence Scale; clinical symptoms and daily life activities were measured using the Blessed dementia scale.
Results: The statistical sample showed a general reduction of 28.30 (SD = 21.6) in their rate of cognitive decline. All groups showed an important impairment in attention, recent verbal memory, recent visual memory, visuo-motor coordination and planning. Remote memory, conceptualization and social norms fell in average range for the three groups. Symptoms presented by patients that interfered with daily life activities were: memory 89%, non-economic productivity 84%, disorientation 82%, mathematics problems 82%, depression 81% and issues relating to money management in 80%.
Conclusions: The three different types of neurocognitive disorder in advanced stages presented specific neuropsychological profiles with no difference among all groups.


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Rev Mex Neuroci. 2014;15