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Federación Mexicana de Ginecología y Obstetricia, A.C.

2014, Number 08

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Ginecol Obstet Mex 2014; 82 (08)

Vulvar carcinoma in situ in 19 year old woman: a case report and literature report

Togo-Peraza JM, Togo-Osuna LR, Montoya-Romero JJ

Language: Spanish
References: 11
Page: 558
PDF size: 487.01 Kb.


ABSTRACT

The vulvar cancer is a rare disease. It´s incidence is about 2.2 cases per 100, 000 women. The presentation of invasive vulvar cancer and in situ vulvar cancer has arrise in it´s presentation with an increse of 2.4% per year. The National Cancer Institute has reported that vulvar cancer has been one of the twelve maliganant tumors that have increased thei incidence.
The following is a case report of a 19 years old woman with diagnose of in situ vulvar cancer found incidentally on the perineal skin during the performing of a uterine curettage, with the diagnosis of abortion.
The treatment consisted in a wide resecction of the perineal skin and residual condilomas and evaporation of vaginal condilomas with laser argon, following vulvar reconstruction. After the surgical treatment 5% imiquimod cream was used in the site of the surgery three times a week for an eight weeks period. Complete remision was achived and there was not early recurrences.


REFERENCES

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  2. Messing MJ, Gallup DG. Carcinoma of the vulva in young women. Obstet Gynecol 1995;86:51-4.

  3. Judson PL, Habermann EB, Baxter NN, Durham SB, Virnig BA. Trends in the incidence of invasive and in situ vulvar carcinoma. Obstet Gynecol 2006;107:1018-22.

  4. Cararach Tur, M. Neoplasia Vulvar Intraepitelial. http:// aepcc.org/download/congresos/xxi/ponencias/cararach_ tur.html. 2009.

  5. Heller DS. Report of a new ISSVD classification of VIN. J Lower Gen Tract Dis 2006; 11: 46-7.

  6. Brown JV, Goldstein BH, Rettenmaier MA, et al. Laser ablation of surgical margins after excisional partial vulvectomy for VIN: effect on recurrence. J Reprod Med 2005; 50:345-50.

  7. Penna C, Fallani MG, Fambrini M, Zipoli E, Marchionni M. CO2 Laser surgery for vulvar intraepithelial neoplasia. Excisional, destructive and combined techniques. J Reprod Med 2002; 47:913-8.

  8. Hillemanns P, Wang X, Staehle S, Michels W, Dannecker C. Evaluation of different treatment modalities for vulvar Intraepitelial neoplasia (VIN): CO2 laser vaporization, photodynamic therapy, excisional and vulvectomy. Gynecol Oncol 2006; 100:271-75.

  9. Holschneider, CH. Vulvar intraepithelial neoplasia. http:// www.uptodate.com/contents/vulvar-intraepithelialneoplasia? source=search_result&search=VIN&selectedT itle=1~24. 2014.

  10. van Seters M, van Beurden M, ten Kate FJ, et al. Treatment of vulvar intraepithelial neoplasia with topical imiquimod. N Engl J Med 2008; 358:1465.

  11. Mathiesen O, Buus SK, Cramers M. Topical imiquimod can reverse vulvar intraepithelial neoplasia: a randomised, double-blinded study. Gynecol Oncol 2007; 107:219.




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