medigraphic.com

2011, Number 26

<< Back Next >>

Hipoc Rev Med 2011; 6 (26)

Presentación clínica, radiológica y patológica de las formas pseudotumorales de esclerosis múltiple. Revisión de la literatura

Núñez-Velasco S, Vargas-Sánchez Á, Castañeda-Moreno V, Zúñiga- Ramírez C, Ruiz-Sandoval JL

Language: Spanish
References: 9
Page: 6-8
PDF size: 146.03 Kb.


ABSTRACT

Pseudotumoral Multiple Sclerosis is a rare variant of multiple sclerosis, who presents demyelinizated lesions bigger than 20 mm, with edema and mass effect. Most of the clinical presentations are multi-symptomatic, being predominant the motor symptoms. Diagnosis is reach by Magnetic Resonance, spectroscopy, and biopsy, trying to discard two of the most comun differentials: acute disseminated encephalomyelitis and low grade astrocitoma. Steroids, plasmapheresis and immunoglobulin are preferred as treatment.


REFERENCES

  1. 1.- Butteriss DJ, Ismail A, Elison DW, Birchall D. Use of serial proton magnetic resonance spectroscopy to differentiate low grade glioma from tumefactive plaque in patient with multiple sclerosis. Br J Radiol 2003;76: 662–5.

  2. 2.- Comi G. Multiple Sclerosis: Pseudotumoral Forms. Neurol Sci (2004) 25:S374–S379.

  3. 3.- Kirayama T, Kataoka H, Toshiaki, et al. Characteristic Neuroimaging in Patients with Tumefactive Demyelinating Lesions Exceeding 30 mm. J Neuroimaging 2010;22:1-9.

  4. 4.- Lucchinetti CF, Gavrilova RH, Metz I, et al. Clinical and radio-graphic spectrum of pathologically confirmed tumefactive multiple sclerosis. Brain 2008;131:1759-1775. 5.- Poser S, Luer W, Bruhn H, Frahm J, Bruck Y, Felgenhauer K. Acute demyelinating disease. Classification and noninvasive diagnosis. Acta Neurol Scand 1992; 86: 579–85.

  5. 6.- Paty DW, Oger JJ, Kastrukoff LF, Hashimoto SA, Hooge JP, Eisen AA,et al. MRI in the diagnosis of MS: a prospective study with comparison of clinical evaluation, evoked potentials, oligoclonal banding, and CT.Neurology 1988; 38: 180–5.

  6. 7.- Kepes J. Large focal tumorlike demyelinating lesions of the brain:intermediate entity between multiple sclerosis and acute disseminated encephalomyelitis: a study of 31 patients. Ann Neurol 1993; 33: 18–27.

  7. 8.- Lin A, Ross DB, Harris K, Wong W. Efficacy of Proton Magnetic Resonance Spectroscopy in Neurological Diagnosis and Neurotherapeutic Decision Making NeuroRx, Vol. 2, No. 2, 2005.

  8. 9.- Capello E, Roccataglioata L, Pagano F, Macardi GL. Tumorlike multiple sclerosis (MS) lesions: neuropathological clues. J Neurosci 2001; 22:S113–6.

  9. 10.- Hynson JL; Kornberg AJ; Coleman LT; Shield L; Harvey AS; Kean MJ. Clinical and neuroradiologic features of acute disseminated encephalomyelitis in children. Neurology 2001 May 22;56(10):1308-12.




2020     |     www.medigraphic.com