medigraphic.com
ISSN 2070-8718 (Print)

2010, Number 3

<< Back Next >>

Rev Cub Gen 2010; 4 (3)

Efficiency of the Prenatal Cytogenetic Diagnosis subprogram in Havana City in the period 2005-2006

Martínez de Santelices CA, Rizo LD, Amor OMT, Fuentes SLE

Language: Spanish
References: 8
Page: 49-53
PDF size: 271.07 Kb.


ABSTRACT

This paper resumes the main results of the project Evaluation of the Efficiency of the Prenatal Cytogenetic Diagnosis in Havana City, finished in 2006. The program was aimed at the detection of the organizational deficiencies of the subprogram, detecting and comparing the differences in organizational principles and deficiencies in the subprogram execution in all municipalities of Havana City province. Topics referring to the behavior of indication criteria and the fetal cytogenetic diagnosis were studied in depth, considering the importance of the risk of cromosomopathies detection in the population. Prenatal cytogenetic diagnosis was indicated in all municipalities mainly to pregnants having 38 to 41 years old. Normal results were obtained for 86,7% of the pregnants having the diagnosis done, while 2,3 % had positive results and in 50 pregnants (3,8%) this result was not conclusive.


REFERENCES

  1. de León ONE. Algunos aspectos del programa de diagnóstico manejo y prevención de enfermedades genéticas y defectos congénitos. [en línea] 2010 [fecha de acceso junio de 2010]. URL disponible en: http://www.sld.cu/sitios/genetica/verpost. php?blog=http://articulos.sld.cu/genetica.

  2. Pimentel BHI GB, Martín CN, Alonso BY, Torres PM, Suárez MU. Diagnóstico Prenatal Citogenético en Camagüey. Resultados de 20 años. Rev Cubana Genet Comunit. 2008;2(3):34-8.

  3. Kowalczyk M SM, Tomaszewska A. Chromosome abnormalities without phenotypic consequences. J Appl Genet. [Review]. 2007;48(2):157– 66.

  4. Lachmann R PG, Moratalla J, Greene N, Nicolaides KH,. Frontomaxillary facial angle in fetuses with spina bifida at 11–13 weeks’gestation. Published online in Wiley InterScience. 2010;36:268-71.

  5. Méndez RLA QM. Diagnóstico Prenatal Citogenético mediante cultivo de amniocitos. Rev Cubana Genet Comunit. 2009;3(1):7-15.

  6. World Medical Association Declaration of Helsinki: ethical principles for medical research involving human subjects. JAMA. 2000 Dec 20;284(23):3043-5.

  7. Barrios MA. Manual de Buenas Prácticas para el Laboratorio de Citogenética. La Habana: Centro Nacional de Genética Médica; 2011.

  8. Benn PA EJ, Fang M, Smith-Bindman R. Changes in the utilization of prenatal diagnosis. Obstet Gynecol. 2004;103(6):1255- 60.




2020     |     www.medigraphic.com