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Revista Cubana de Genética Comunitaria

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2010, Number 3

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Rev Cub Gen 2010; 4 (3)

Hemoglobins S and C carriers in pregnants of Guantánamo province, 2005-2009

Leyva FO, Martínez RA, Calvo DMM, Martín RN, Rubinos VA
Full text How to cite this article

Language: Spanish
References: 6
Page: 54-56
PDF size: 264.97 Kb.


Key words:

sickle-cell anemia, carriers frequency, inquiry.

ABSTRACT

This investigation was carried out with the purpose of determining the frequency of carrier pregnants of S and C hemoglobins in Guantánamo province, from January 2005 to December 2009. A total of 35 266 pregnants were studied from the data available in the registers of the Hematoglobinopathy of the Provincial Center of Medical Genetics, calculating the frequency of carriers. The frequency of HbAS carriers in the province turned out to be, with the most affected municipalities being Niceto Pérez (8,20 %), El Salvador (6,70%)and Guantánamo (6,39%). The HbAC carriers frequency in the province was equal to 0,90%, standing out Niceto Pérez (1,23%) , Yateras (1,15 %) and Manuel Tames (1,11%). These results are higher than those reported for the whole country and are a consequence of a greater number of African descendants in these zones and of the formation and union of couples.


REFERENCES

  1. Nussbaum RL, Mc Innes RR, Wilard HF. Thompson and Thompson. Genetica en Medicina. 7ª Edición. Barcelona (España): Elsevier; 2008.

  2. Martín Ruiz MR, Lemus Valdéz M, Marcheco Teruel B. El Programa Cubano de prevención de Anemia Falciforme. Resultados del período 1990-2005. Rev. Cubana Genet Comunit. 2008;2(2):59-66.

  3. Domínguez Mena M, Viñales Pedraza MI, Santana Hernández ME, Morales Peralta E. Pesquisaje y dilema del asesoramiento genético en parejas de riesgo de anemia a hematíes falciformes. Rev Cubana Med Gen Integr. 2005;21(1-2).

  4. Svarch E. Fisiopatología de la Drepanositosis. Rev Cub Hemat Inmunol y Med Trans. 2009;25(1).

  5. Villares Alvares I, Rios Araujo TB, Fernández Ávila JL, Cabrera Samora M. Manifestaciones oculares en adultos con drepanocitosis de la provincia de Cienfuegos. Rev Cub Hemat. Inmunol y Med Trans. 2009;25(2):75-85.

  6. Alvares Guerra E.D, Fernández García A. La anemia de hematíes falciformes: investigaciones para el diagnóstico y tratamiento[en línea] 2007 [Fecha de acceso 10 de diciembre de 2009].URL disponible en: http://www.santiago.cu/cienciapc/ numeros/2007/4/articulo1.htm




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Rev Cub Gen . 2010;4