Mercado U, Jaramillo-Ramírez HJ

Language: Spanish
References: 7
Page: 502-505
PDF size: 480.00 Kb.

ABSTRACT

This paper reports the case of a 22-year-old woman who when she was 15 was seen in the Rheumatology service because of erosive deforming arthropathy and productive cough. Her laboratory showed ANA 1:320, anti-cyclic citrullinated peptide 449 IU/mL (normal value: 5.0), a specific highly marker for rheumatoid arthritis, rheumatoid factor 1:64 IU/ mL), normal titers of serum immunoglobulins and acid fast bacilli were not detected. Five years previous, she had been diagnosed as having lupus on the basis of polyarthritis, seizures, serositis and proteinuria, and later received treatment against tuberculosis. In March 2013, at 22 years, she was seen due to constant cough and chest pain. CT scan of the thorax revealed an anterior mediastinal mass. A CT-guided biopsy was done. Diagnosis was reported as type B1 thymoma (World Health Organization Classification). Immunohistochemistry showed positivity for cytokeratine, CD3 and Tdt. A diagnosis of rhupus associated with thymoma was established.

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