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ISSN 2070-8718 (Print)

2011, Number 1

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Rev Cub Gen 2011; 5 (1)

Predictive value of nuchal translucence as an indirect marker of congenital defects for pregnants in Havana

Pérez TJ, Martínez de Santelices CA, Oliva RJA, Bacallao GJ

Language: Spanish
References: 17
Page: 1-14
PDF size: 223.20 Kb.


ABSTRACT

An analytical observational transversal study was carried out including pregnants with pregnancy times from 10,0 to 14,0 weeks, all of them taken care of in the provincial Center of Medical Genetics in Havana. All fetuses of these pregnants, included in the period from January 2001 to January 2009, had their nuchal translucence measured. A statistical relation between the number of congenital defects and the increase in the measure of nuchal translucence was found in the pregnants under study. Its predictive value was evidenced by means of the relative operative characteristic curves. A predictive probability was calculated including the value of nuchal translucence, gestational age and the cephalic−caudal length that showed a greater predictive value than the nuchal translucence by itself, a fact that must be taken into account when estimating the specific risk of each pregnant. A least risk range of values for nuchal translucence was obtained by applying the classification trees method.


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