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ISSN 2070-8718 (Print)

2011, Number 2

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Rev Cub Gen 2011; 5 (2)

Genetic etiology in the origin of mental disability in the Republic of Ecuador

Lardoeyt FR, Rodríguez GH, Pérez EO, Jijón AM, Rodríguez PR, Hernández MH, Best CS, Gámez FM

Language: Spanish
References: 16
Page: 44-49
PDF size: 803.54 Kb.


ABSTRACT

Intellectual disability is a serious health problem prioritized in many countries. Within the etiological group of causes genetic ones, mainly those hereditary, represent 50 % of the cases. A total of 68 687 individuals with intellectual disabilities were studied in the four regions of the Republic of Ecuador through a cross-sectional descriptive design study in the period June 2009 to December 2010 with the aim of determining the prevalence of the genetic etiology of intellectual disability. Prenatal genetic etiology accounted for 28,45 % of intellectual disability, and prenatal environmental evidence and nonspecific prenatal accounted for 6,61 % and 12,65 % respectively. Prenatal genetic etiology accounts for nearly 30 % of people surveyed in the mountains, while the largest percentage of nonspecific prenatal was found to be in the coast region. The prenatal environmental category was larger in the eastern region, with 7,60 %. The multifactorial etiology predominated, followed by chromosomal causes. The monogenic cause predominated in the Amazonia, showing the lowest occurrence frequency.


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