Banderas HR, Labori RJR, Silva GG

Language: Spanish
References: 6
Page: 113-116
PDF size: 442.15 Kb.

ABSTRACT

A descriptive cross-sectional study was carried out in Manabí province, Republic of Ecuador during 2010, with the objective of characterizing some clinical-genetic and epidemiologic variables regarding Down’s syndrome. The universe under study was formed by 1 017 persons diagnosed with the syndrome. It was found that the prevalence rate equalled 8,5 per 10 000 inhabitants, the 0 to 19 years old group being the largest one and also that 51,8 % of cases had a moderate intellectual disability and in 40,32 % cases the mother was less than 35 years old at conception.. This study evidenced that in this region the Down’s syndrome largest prevalence rate is found in the optimum ages for conception and also that this genetic disease is accompanied by a moderate to severe intellectual disability and a greater degree of partial dependency in the patients.

REFERENCES

1. M.I. Tejada. Retraso mental de origen genético. Presentación de la Red GIRMOGEN. Rev Neurol. 2006;42(Supl 1):S1-S6.

2. Miriam Portuondo Sao, Araceli Lantigua Cruz, Roberto Lardoeyt Ferrer, Denia Tassé Vila. Caracterización etiológica del retraso mental en una población del municipio Marianao. Rev Cubana Genet Comunit. 2007;1(1):20-4.

3. Jijón Milton. Alarmantes datos del síndrome Down en Ecuador. Periódico informacion@ecuadorenvivo.com. [en línea] 2010 [fecha de acceso 12 de noviembre de 2010]. URL disponible en: http://www.eldiario.com.ec/noticias-manabiecuador/ 171687-cifras-de-personas-con-sindrome-de-down-aumenta-en-el-pais/

4. American Academy of Pediatrics Committee on Genetics. Health Supervision for Children with Down syndrome. Pediatrics. 2001;107(2):442-9.

5. American College of Obstetricians and Gynecologists (ACOG). Your Pregnancy and Birth. 4ta ed. Washington DC: ACOG; 2005.

6. María Emilia Ferrero Oteiza, Francisca Alonso Lotti, Isidro Cendán Muñiz, Joel Roca Ortiz, Andrés Pérez Valle, María C. Estévez Lloret. Tendencias del síndrome de Down en Cuba. Su relación con edad materna y tasa de fecundidad. Rev Cubana Pediatr.1998;70(3):141-7.