Fajardo-Ochoa F, Olivas-Peñuñuri MR, Castillo-Aldaco JD

Language: Spanish
References: 15
Page: 57-62
PDF size: 1012.75 Kb.

ABSTRACT

Introduction: Coccidioides immitis is a dimorphic soil fungus that commonly causes a mild, self-limited respiratory illness in children and adults within the endemic area of the southwestern United States and northern Mexico. The disease is rarely reported in neonates and infants. When it does occur in this age group, the disease is devastating and frequently lethal.
Case Report: We report a case history of an infant 20 days old having a febrile syndrome, respiratory distress and irritability. Quickly have a torpid evolution, progressive respiratory distress, intermittent high fever and difficult to control it. Chest radiographs demonstrating diffuse, coarse, nodular infiltrates and dense consolidation areas throughout both lungs. No response to treatment of various antimicrobial agents and anti-tuberculosis drugs. Died of septic shock, the autopsy revealed pulmonary and lymphatic nodes infection with Coccidioides spp and spread to the liver, spleen, pancreas and bone marrow.
Conclusion: Neonatal pulmonary coccidioidomycosis is a rare event. Aspiration of arthrospores of C. immitis during childbirth is the most likely way to acquire the agent without discarding the possibility of acquisition by environmental exposure to dust. This diagnosis should be considered in infants with extensive bilateral nodular infiltrate.

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