Martínez FCM, Granados SE, Sandoval GC, Zepeda CR, Elizalde AI, Casian CGA

Language: Spanish
References: 10
Page: 281-286
PDF size: 317.12 Kb.

ABSTRACT

Introduction: Malformations may be due to extrinsic, teratogenic or infectious factors. Etiology is unknown in more than 60% of the cases, while chromosopathy refers only to 6% and autosomic cases represent 7.5%. Multi-factor inheritance represents 20 percent of the cases and all chemical and environmental teratogenics, infections, cases due to radiation a system illnesses account for 3.5%. Many of them are incompatible with live or face critical conditions.
Material and Methods: In the period extending from January 2001 to 2003, a pediatric population from the neonatology, emergency room and intensive care units from the Hospital 1o de Octubre was chosen. All were clinically assessed by the Pediatric Neurology area. Those that were included in the protocol underwent Computerized Tomography and Magnetic Resonance Images.
Results: Thirteen subjects were included, of which 53.8% presented external malformations of the neural track, 23% West syndrome, and 46% had cellular migration alterations.
Conclusions: The clinical impact of early diagnosis of brain dysgenesis, and the impact in the patient’s prognosis justifies the use of the main image diagnosis methods. There are many reasons why patients with malformations do not get a timely diagnosis, amongst them are that at least 15% are referred to a second level healthcare center that lacks Pediatric Neurology and CT services.

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