de la Torre HCA, Marcheco TB

Language: Spanish
References: 6
Page: 31-35
PDF size: 481.59 Kb.

ABSTRACT

The subprogram for the detection of sickle-cell anemia carriers in Cuba comprises the prevention of SS and SC hemoglobins by establishing procedures to identify high-risk couples, genetic counseling, molecular studies for prenatal diagnosis and selective interruptions to affected fetuses as a voluntary selection of affected couples. An analytic quasi-experimental study of programs with a retrospective analysis of the main subprogram functioning indicators was carried out in Havana from 2007 to 2010. Data was obtained from the statistical yearbooks published by the Ministry of Public Health. A rate of 2,88 per 10 000 born alive having sickle-cell disease, undetected by the subprogram was confirmed, as well as a reduction of the expected 4,84 per 10 000 born alive, mainly due to pregnancy interruptions after prenatal diagnosis. Also 3 770 high-risk pregnant patients were detected and 91 % of their spouses were also studied. The results of the subprogram indicators in the evaluated period can be considered as being a sample of the success of the implementation, development and continuous improvement of the National Genetics Program in the country.

REFERENCES

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