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Instituto de Seguridad y Servicios Sociales de los Trabajadores del Estado
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2014, Number 4

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Rev Esp Med Quir 2014; 19 (4)

Correlation between amniotic fluid cultures and cervicovaginal secretions in patients with preterm delivery menace

Serrano BMÁ
Full text How to cite this article

Language: Spanish
References: 10
Page: 405-408
PDF size: 419.83 Kb.


Key words:

amniocentesis, amniotic fluid.

ABSTRACT

Background: Amniotic fluid has a bacteriostatic effect that inhibits bacterial growth, maintains a sterile environment for the fetus, and avoids the growth of vaginal microorganisms. Amniocentesis is a procedure to obtain amniotic fluid, allowing the study of the fetus and the amniotic environment.
Objective: To know the correlation between microorganisms found in cultured amniotic fluid obtained by amniocentesis with those reported in cultures of cervicovaginal secretions in patients with a diagnosis of preterm labor.
Patients and methods: A prospective cross-sectional study in which cultured amniotic fluid obtained by amniocentesis from 84 pregnant patients with a diagnosis of preterm labor between 24-34 weeks gestation at the Hospital Regional Adolfo López Mateos during the months from January to December 2012. The blood agar culture media, and Sabouraud agar were used, as well as the culture of cervicovaginal secretions which is looking forward to correlate the findings of both studies
Results: We found that 65 patients (40.6%) were nulliparous and 19 (59.4%) multiparous. The results of cultures of amniotic fluid were negative in all 84 patients (100%). Normal flora was found in cultures of cervicovaginal secretions in 39 (46.4%). In 45 cases (53.5%) positive cultures were reported: 40 cases (88.8%) with Candida albicans, and 5 (11.1%) with Escherichia coli.
Conclusions: no correlation was observed between the presence of microorganisms that grew in the amniotic fluid with those found in cervicovaginal secretions. There are other simpler and cheaper tests that can be performed quickly and may be more useful in the early diagnosis of amniotic infection.


REFERENCES

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  2. Park CW, Kim SM, Park JS, Jun JK, Yoon BH. Fetal, amniotic and maternal inflammatory responses in early stage of ascending intrauterine infection, inflammation restricted to chorio-decidua, in preterm gestation. J Matern Fetal Neonatal Med 2014;27(1):98-105.

  3. Lee SY, Park KH, Jeong EH, Oh KJ, Ryu A, Kim A. Intraamniotic infection/inflammation as a risk factor for subsequent ruptured membranes after clinically indicated amniocentesis in preterm labor. J Korean Med Sci 2013;28(8):1226-32.

  4. Combs CA, Gravett M, Garite TJ, Hickok DE, et al. Amniotic fluidinfection, inflammation, and colonization in preterm labor with intact membranes. ProteoGenix/Obstetrix Collaborative Research Network. Am J Obstet Gynecol 2013;23.

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Rev Esp Med Quir. 2014;19