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2013, Number 3

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Dermatología Cosmética, Médica y Quirúrgica 2013; 11 (3)

Nelson’s Syndrome. Report of one case

Chang P, Román V, Monterroso MA, Castro BML, Cordón C, Rivera S
Full text How to cite this article

Language: Spanish
References: 12
Page: 199-202
PDF size: 184.46 Kb.


Key words:

melanodermia, melanonychia, pituitary adenoma, Cushing Syndrome.

ABSTRACT

We report a 27 year-old woman with Cushing Syndrome, after bilateral adrenalectomy, develop generalized hypermigmentation and pituitary adenoma, (Nelson’s Syndrome) due to rarity of the disease in the present time and the remarkable clinic presentation we consider an interesting case.


REFERENCES

  1. Assié G, Bahurel H, Bertherat J, Kujas M, Legmann P, Bertagna X. “The Nelson’s syndrome revisited”. Pituitary 2004; 7(4): 209-215.

  2. Nelson DH, Meakin JW, Dealy JB, et al. “ACTH-producing tumor of the pituitary gland”. N Engl J Med 1958; 259(4): 161-164.

  3. Munir A., Newell-Price J., “Nelson’s Syndrome”. Arg Bras Endocrinol Metabol 2007; 51(8): 1392-1396.

  4. Casulari LA, Naves LA, Mello PA, Pereira Neto A, Papadia C. “Nelson’s syndrome: complete remission with cabergoline but not with bromocriptine or cyproheptadine treatment”. Horm Res 2004; 62(6): 300-305.

  5. Tosti A, Baran R, Dawber RPR. “The nail in systemic diseases and druginduced changes”, In: Baran R, Dawber RPR, Diseases of the Nails and Their Management. Blackwell Science, 1996.

  6. Wilson T, Desikan V, Chrousos G, Lafferty A. “Nelson’s Syndrome Article”. EJournal of Medicine Specialists, Medscape. Mar 2009: endocrinology section. (http://emedicine.medscape.com)

  7. Weismann K, Graham RM. “Systemic Disease and the skin”. In: Rook A, Wilkinson DS, Ebling FJG, Text Book of Dermatology. Blackwell Science, 1998.

  8. Pivonello R, Faggiano A, Di Salle F, Filippella M, Lombardi G, Colao A. “Complete remission of Nelson’s syndrome after 1-year treatment with cabergoline”. J Endocrinol Invest. 1999; 22(11): 860-865.

  9. Kobayashi T, Kida Y, Mori Y. “Gamma knife radiosurgery in the treatment of Cushing disease: long-term results”. J Neurosurg 2002; 97(5): 422-428.

  10. Vik-Mo EO, Oksnes M, Pedersen PH, Wentzel-Larsen T, Rodahl E, Thorsen F, Schreiner T, Aanderud S, Lund-Johansen M. “Gamma knife Stereotactic radiosurgery of Nelson syndrome”. Eur J Endocrinol 2009; 160(2): 143-148.

  11. Moyes VJ, Alusi G, Sabin HI, Evanson J, Berney DM, Kovacs K, Monson JP, Plowman PN, Drake WM. “Treatment of Nelson’s syndrome with temozolomide”. Eur J Endocrinol 2009; 160(1): 115-119.

  12. Jadresic A, “Tratamiento médico de los tumores hipofisiarios productores de corticotrofina y tirotropina”. Rev chil neuro-psiquiatr 1997; 35(1): 63-67.




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Dermatología Cosmética, Médica y Quirúrgica. 2013;11