González GKI, Alcalá PD, Medina BA, Torres GS

Language: Spanish
References: 12
Page: 221-226
PDF size: 270.96 Kb.

ABSTRACT

Background: Primary cutaneous lymphomas are a heterogeneous group of T- and B-cell lymphomas that show a wide range of clinical, histology, immunophenotype and prognostic aspects. Cutaneous T-cell lymphomas represent 65%, primary cutaneous B cell lymphomas approximately 25% and 10% are mixed or not well classified cases.
Objective: To determine the epidemiologic characteristics of patients with diagnosis of cutaneous lymphoma attending the Centre of Dermato-Oncology “Pascua”.
Material and Methods: A transverse, retrospective, observational and descriptive study was done in a twenty year period. We found 140 patients with the clinical diagnosis of cutaneous lymphoma; 65 patients were excluded from the study, 53 because no histopathologic study was found and 12 because they were just classified as a lymphoproliferative disorder.
Results: 75 cases of lymphoma were confirmed (0.82%) at the Clinic of Dermato-Oncology; 70.7% were cutaneous T-cell lymphoma and 29.3% cutaneous B-cell lymphoma. We found a predominance of male patients (58.7%); affecting trunk (29.4%) extremities (28.2%); and head (13.6%). Evolution ranged from less than one–year in 37.3%, from one to five years in 38.7% and more than five years in 24% . The group with the triple treatment had a cure rate of 71%, and those with the conventional treatment 36% (P = 0.1). The group with ungueal dystrophy and negative KOH had a cure rate of 20.8% (P = 0.000).
Conclusions: Epidemiologic features in our patients are similar to those reported in the literature, with a male predominance, higher frequency of affection on the trunk and extremities and a history of less than one year.

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