Reyes MG, Romero GAL, Alcántara HP, Mata MMP, Parraguirre S, Vega-Memije E

Language: Spanish
References: 14
Page: 80-87
PDF size: 167.43 Kb.

ABSTRACT

Background: A skin cancer prevalence of 13.6% has been reported by the National Malignant Tumors Registration in Mexico.1 Skin cancer includes a group of tumors with malignant biologic behavior. They present differences on their invasion ability, metastasis tendency and mortality rate.
Objetive: To obtain the epidemiologic features of skin cancer with their clinical and histological characteristics in population attending the Dermatology and Pathology Services of Dr. Manuel Gea González General Hospital.
Material and Methods: A transversal, retrospective, descriptive and observational study was carried out in 8,821 cases of patients with skin biopsy that were previously registered in the Dermatopathology and Pathology Services from June 1995 to June 2005. Descriptive statistics and KAPPA agreement analysis to validate results were used.
Results: 1,326 cases were included, 67% diagnosed with basal cell carcinoma, 19% squamous cell carcinoma, 8% melanoma and 6% with other types of skin cancer. Females were the most frequently affected (58.7%), 43.2% within an age range of 56 to 75 years, 43.2% were older than 75 years-old, and 25% were younger than 56 yearsold. Head and neck were the most affected areas (78.7%), and trunk represented only 6.9%. Clinical and histological diagnostic correlation was 76% for basal cell carcinoma, 60% for squamous cell carcinoma and 81% for melanoma.
Conclusions: Prevalence of basal cell carcinoma was smaller than that reported in literature (67% vs. 77%). The distribution for gender was similar except for squamous cell carcinoma, which is usually more frequent in males, and age and topography showed similar characteristics. The correlation between clinical and histological diagnoses was good/perfect for basal cell carcinoma and melanoma, and adequate for squamous cell carcinoma.

REFERENCES

1. Registro Histopatológico de Neoplasias Malignas, 1a ed., 2001

2. Arenas R. Dermatología Atlas, diagnóstico y tratamiento. 2a ed. McGraw Hill, México, 2003; 502-534

3. Gay C. Malignant lesions in dermatology, Clinics in Family Practice. 2003, Vol. 5(3): 54-61

4. Peniche J. Tumores de la piel, en: Saúl A, editor. Lecciones de dermatología, México, 2000; 539-592

5. Peniche AC. Carcinoma epidermoide PAC-Dermatología México: Intersistemas, 2002; 29-38

6. Mohar A. Epidemiología descriptiva de cáncer en el Instituto Nacional de Cancerología de México. Salud Pública Mex 1997; 39: 253-258

7. Jemal A, Murray T, Samuels A. CA Cancer. J Clin 2003; 53: 5-26

8. González S, Gutiérrez RM, Medina A. El carcinoma epidermoide en el Centro Dermatológico Pascua. Dermatol Rev Mex; 2003; 47(2): 61-65

9. Calderón Rocher C, Gutiérrez RM, Ramos A et al. Correlación entre el diagnóstico clínico e histopatológico de las neoplasias más importantes en el servicio de oncología del Centro Dermatológico Pascua. Dermatología Rev Mex 2003; 47(1): 1-4

10. Saucedo AP, Gutiérrez RM, Medina A. Cáncer de piel en el Centro Dermatológico Pascua. Estudio epidemiológico de 10 años. Dermatol Rev Mex 2005; 49: 231-9

11. Kalter DC, Goldberg LH. Darkly pigmented lesions in dark skinned patients. J Dermatol Surg Oncol 1984; 10: 876-881

12. Dewberry Ch. Skin cancer in elderly patient. Dermatol Clin 2004; 22: 93-96

13. Rowe DE, Carroll RJ, Day CL. Long-term recurrence rates in previously untreated (primary) basal cell carcinoma: implications for patient follow-up. Journal of Dermatologic Surgery and Oncology 1989; 15(3): 315-328

14. Committee on Guidelines of Care. Guidelines of care for cutaneous squamous cell carcinoma. Task Force on Cutaneous Squamous Cell Carcinoma. Journal of the American Academy of Dermatology 1993; 28(4): 628-631