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ISSN 0185-3252 (Print)
Revista de la Asociación Médica del Centro Médico ABC

2015, Number 1

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An Med Asoc Med Hosp ABC 2015; 60 (1)

Efficacy of nebulized dexamethasone for the treatment of postintubation sore throat

Cruz VJA, Ochoa AG, Montoya PTG, Valdez OR, Gómez MC

Language: Spanish
References: 21
Page: 19-23
PDF size: 212.74 Kb.


ABSTRACT

Postoperative sore throat is common in patients undergoing endotracheal intubation, and occurs in 21-65% of patients; this constitutes an important factor in the patient satisfaction with the anesthetic procedure. Purpose: To evaluate the efficacy of nebulized dexamethasone for the treatment of postintubation sore throat. Methods: Thirty-nine people were included and randomly divided into three groups: group 1: dexamethasone 8 milligrams; group 2: dexamethasone 16 milligrams; group 3: placebo. Patient assessment of sore throat was made using a visual analogue pain scale before the nebulization, immediately after the nebulization and sixty minutes later. Results: The 16 milligrams group showed a greater reduction in sore throat at 60 minutes compared with placebo (p = 0.067). When comparing baseline data against sixty minutes in the three groups, there was a large effect size (0.86) for the dexamethasone 16 milligram group versus small (0.48) for the dexamethasone 8 milligram group. Conclusion: Administration of nebulized dexamethasone is effective for the treatment of sore throat, which showed a trend toward statistical significance; but requires a larger sample size to demonstrate significance. It is important to point out that our results should be interpreted with caution until larger population-based studies can be performed.


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