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2015, Number 1

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Rev Hematol Mex 2015; 16 (1)

Multiple myeloma in a young patient

Baldovinos-Naranjo L, Rivera-Trujillo A, Hernández-Rodríguez S, Velázquez-Delgado G, Villaseñor-Aguirre Morelos Vil, Gómez-Guijosa MÁ
Full text How to cite this article

Language: Spanish
References: 20
Page: 97-101
PDF size: 512.96 Kb.


Key words:

symptomatic multiple myeloma, M protein, beta 2 microglobulin, CD138, kappa chains, age.

ABSTRACT

Multiple myeloma is a haematological malignancy with the common denominator in the production of M protein, and a variety of clinical presentation that throughout history has required adjustments to the definition of it, the vast majority of cases have been reported in the seventh decade of life, and less than 1%, reported in patients under 30 years, without finding reports of patients younger than 20 years in our country. This paper reports the case of an 18-year-old female patient previously diagnosed with primary hyperthyroidism and chronic evolution of anemic syndrome with IgG kappa monoclonal gammopathy, without lytic lesions, hypercalcemia, or renal failure, with plasma cells in bone marrow, without evidence of extramedullary plasmacytomas, in who the diagnosis of symptomatic multiple myeloma was established in conjunction with high beta 2 microglobulin, positive immunohistochemical CD138, kappa chains in the bone biopsy. The presentation differs from that reported for this age group.


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Rev Hematol Mex. 2015;16