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Revista Cubana de Oftalmología

ISSN 1561-3070 (Electronic)
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2014, Number 4

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Rev Cub Oftal 2014; 27 (4)

Ophthalmological manifestations of epidermolysis bulosa

Díaz RME, Pérez PZ, Escalona LET, Noriega MJL, Castillo PAC, Márquez MS
Full text How to cite this article

Language: Spanish
References: 10
Page: 619-625
PDF size: 114.78 Kb.


Key words:

epidermolysis bulosa, genodermatosis, corneal scarring.

ABSTRACT

Epidermolysis bulosa is defined as genodermatosis involving a heterogenous group of blistering diseases in the skin and the mucosas, located in the epidermal basal membrane and the basal layer of the stratified, keratinized or mucosal epithelium, with resulting fragility of the skin and variable severity in its clinical presentation. The most common eye findings of this disease were described and shown. The treatment of epidermolysis bulosa should be multidisciplinary, paying special attention to the outer ocular surface to prevent alterations that may affect the vision.


REFERENCES

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  2. Matsumoto Y, Dogru M, Tsubota K. Ocular surface findings in Hallopeau-Siemens subtype of dystrophic epidermolysis Bullosa: report of a case and literature review. Cornea. 2005 [citado 28 de marzo de 2014];24(4):[aprox 4 p.]. Disponible en: http://journals.lww.com/corneajrnl/pages/articleviewer.aspx?year=2005&issue=05 000&article=00019&type=abstract

  3. Featherstone C. Epidermolysis Bullosa: from fundamental molecular biology to clinical therapies. J Invest Dermatol. 2007 [citado 28 de marzo de 2014]; 127:[aprox 12 p.]. Disponible en: http://www.nature.com/jid/journal/v127/n2/full/5700731a.html

  4. Salas-Alanis JC. Las epidermólisis bullosas. El proyecto DebRA. Med Cutan Iber Lat Am. 2007;35(4):165-6.

  5. Pérez L, Urbina F, Roa J, Díaz Ch, Zambrano F. Aplasia cutis congénita: a propósito de cuatro casos. Rev Chil Pediatr. 2001;72(4):345-51.

  6. Serra Ortega A, Sánchez Pérez OI, Clavel Isás D, Moreno Romo E. Epidermólisis bullosa, aplasia cutis congénita y atresia pilórica. Hallazgos histopatológicos en un neonato. Patología Autópsica. 2009;23:45-55.

  7. Fine JD, Johnson LB, Weiner M, Stein A, Cash S, Deleoz J, et al. Eye involvement in inherited epidermolysis Bullosa: experience of the National Epidermolysis Bullosa Registry. Am J Ophthalmol. 2004 [citado 28 de marzo de 2014];138(2):[aprox 3 p.]. Disponible en: http://www.ajo.com/article/S0002-9394%2804%2900373- 3/abstract

  8. Fine JD, Eady RA, Bauer EA, Bauer JW, Bruckner-Tuderman L, Heagerty A, et al. The classification of inherited epidermolysis Bullosa (EB): Report of the Third International Consensus Meeting on Diagnosis and Classification of EB. J Am Acad Dermatol. 2008 [citado 28 de marzo de 2014];58(6):[aprox 4 p.]. Disponible en: http://www.jaad.org/article/S0190-9622%2808%2900208-9/abstract

  9. Khan AO. Corneal ulcer in a young child with autosomal recessive epidermolysis Bullosa. J Pediatr Ophthalmol Strabismus. 2006;43(6):370-2.

  10. Tong L, Hodgkins PR, Denyer J, Brosnahan D, Harper J, Russell- Eggitt I, et al. The eye in epidermolysis Bullosa. Br J Ophthalmol. 1999 [citado 28 de marzo de 2014];83(3):[aprox 4p.]. Disponible en: http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1722980/




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Rev Cub Oftal. 2014;27