Gloria QSI

Language: Spanish
References: 21
Page: 77-81
PDF size: 299.07 Kb.

ABSTRACT

Background: The palatine tonsils, adenoids and lingual tonsils compose de Waldeyer’s ring and are part of the mucosa-associated lymphoid tissue (MALT). This ring of lymphoid tissue is located at the entrance of the upper respiratory tract. As such, the tonsils and adenoids are the first line of defense for protection to the lower respiratory tract and the gastrointestinal tract, and for development of antigenic memory from de host. Tonsils and adenoids produce immunoglobulins since fetal stage, but they do not gain importante levels until birth. They produce all types of immunoglobulins, but mostly IgG and IgA. The most important immunologic activity is developed between 3 and 11 years of life, suffering an involution after puberty. It is proven that maturation of tonsils and adenoids and the external antigenic stimulus are the main factors in the production increase. Serum levels of IgA and IgG immunoglobulins have been studied over the years, especially after adenotonsillectomy and in this way determine the immunological impact in these patients.
Objectives: To determine and compare pre-and postoperative serum immunoglobulin A levels in pediatric patients after adenotonsillectomy in the Pediatric Otolaryngology service at the Hospital para el Niño, Instituto Materno Infantil del Estado de México.
Material and method: A prospective, quasi-experimental, longitudinal study. In this research project the immune response in pediatric patients after adenotonsillectomy was assessed by determining serum levels of immunoglobulin A before and after surgery.
Results: Comparing serum IgA before and after adenotonsillectomy, they were significant with a paired t 0.0001. Neither IgA postoperative values were below the normal range and 4 patients continued high levels up to 6 weeks after surgery.
Conclusions: Serum IgA levels in pediatric patients after adenotonsillectomy decreased without causing immusuppression in patients.

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