2015, Number 2
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Alerg Asma Inmunol Pediatr 2015; 24 (2)
Churg-Strauss: case report
Azamar JAA, García DM, Rodríguez GM, Mendoza HDA, Escamilla QC
Language: Spanish
References: 32
Page: 68-72
PDF size: 262.88 Kb.
ABSTRACT
Churg-Strauss syndrome, also known as allergic granulomatous angiitis, is defined as a small-vessel vasculitis which involves lungs, peripheral nerves, skin, and, less frequently, the heart and gastrointestinal tract. The etiology is unknown and its diagnosis problematic, with clinical findings varying with illness phase. Churg-Strauss syndrome characteristically presents with asthma, allergic rhinitis and blood eosinophilia; microscopically, the typical triad is necrotizing vasculitis, the presence of extravascular granulomas with necrosis and predominant extravascular eosinophils. First described by Churg and Strauss in 1951, it remains as a rare disease, which predominantly presents in adulthood, so information in children are sparse. In 1984, Lanham et al suggest diagnostic criteria for its diagnosis; after that, the American College of Rheumatology proposes six criteria for its clasification. However, little is known about childhood treatment in Churg-Strauss syndrome. An early diagnosis improves significantly its prognosis. We present the case of a 13-year-old female patient with poor control asthma and the diagnosis of Churg-Strauss syndrome.
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