Vásquez-Gutiérrez E, Valdez-Borrel R, Cantú-Reyes J, Martinez-Zurita CM, Garza-Rendón D

Language: Spanish
References: 11
Page: 45-51
PDF size: 301.26 Kb.

ABSTRACT

Introduction. Receptor encephalitis Anti -N - methyl -D - aspartate (NMDA ) is an entity recently described as paraneoplastic syndrome. Initial reports of a syndrome characterized by psychiatric manifestations , seizures and coma were published in 2005.
Case Presentation. Female 13 years old, you start to have headache condition and behavioral changes and decreased consciousness requiring ventilatory support management starting with neuroprotective steroid and gamma globulin were unsuccessful . During the physical examination dependent mass is palpable right ovary . Applying serum anti- NMDA being positive right oophorectomy left salpingo + ovarian biopsy was performed. 7 days postoperative mechanical ventilation is withdrawn, the department of pathology reports bilateral mature teratoma, second surgery is performed , making left oophorectomy . The patient evolved toward improvement . Graduated after 3 months of hospital management . Currently asymptomatic patient without convulsive events , perform normal physical activities without medical treatment.
Discussion. In global and national literature the frequency is less than 0.5/100 , 000 per year. The literature mentions that paraneoplastic limbic encephalitis associated with ovarian teratoma is curable by surgical resection

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