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2015, Number 3

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Rev Mex Pediatr 2015; 82 (3)

Characteristics of neonatal sepsis in a Neonatal Intensive Care Unit of private care

Marín-Romero M, Iglesias-Leboreiro J, Bernárdez-Zapata I, Rendón-Macías ME

Language: Spanish
References: 16
Page: 93-97
PDF size: 275.04 Kb.


ABSTRACT

Neonatal sepsis has a high death rate. Evaluate the characteristics of its clinical presentation allows to establish control measures. Objectives: To describe the panorama of sepsis events in a neonatal therapy unit, with regard to their classification, early or late, and causal agents. Analyze the behavior of infection according to the newborns degree of maturity. Material and methods: We recovered data from clinical records of all the events of sepsis in a private care NICU during seven years and we analyzed them. For this study, we defined sepsis according to the criteria of the Centers for Disease Control and Prevention (CDC) in the United States, and reviewed the results of isolates of pathogens. Results: A total 712 episodes of neonatal sepsis were identified, 650 (91.3%) corresponded to early sepsis and 62 (8.7%) to late sepsis. There were 31 isolates of pathogens, 12 (1.8%) among the 650 cases of early sepsis and 19 (30.6%) of the 62 neonates with late sepsis (p ‹ 0.001). This proportion varied according to the gestational age, being always more frequent the positive cultures in late sepsis. Gram-positive bacteria were obtained in 23 septic neonates, Gram-negative in five cases and fungi were isolated in three newborn infants. Conclusions: In this study, we observed an increased frequency of early sepsis, with few isolates of infectious agents. The likelihood of positive cultures was higher in late sepsis and in extremely premature septic neonates.


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