Arébalo-López M, Urbina-Vázquez AG, Lemus-Sandoval J, Cárdenas-Membrila G

Language: Spanish
References: 13
Page: 626-632
PDF size: 462.70 Kb.

ABSTRACT

Background: Rhabdomyolysis is a disorder characterized by the breakdown of skeletal muscle tissue and leakage of intracellular content into the bloodstream, which can lead to acute kidney injury and death. The clinical presentation varies from asymptomatic elevation of creatine phosphokinase (CPK) to risk of disseminated intravascular coagulation. Laboratory testing is more sensitive determination of muscle enzymes.
Case report: Male 59-year-old who went to private medical service with abdominal pain associated with constipation, They prescribed fenoverine (200 mg/12 h), which decreased their symptoms type. A day later has muscle pain in the pelvic limbs, generalized weakness and arthralgia to become disabling. The patient was attended in the emergency department of this hospital. In the interrogation comment decreased urinary flow and redness of it. Laboratory studies reported: leukocytes 13,000/mm³, hemoglobin 18.10 g/dL, hematocrit 53%, platelets 225,000/mm³, glucose 97 mg/dL, BUN 47.5 mg/dL, urea 102 mg/dL, serum creatinine 5.23 mg/dL, Na 137 mEq/L, K 4.5, mEq/L, Cl 102 mEq/dL, CPK 122.988 mg/dL, myoglobin ›4,060, CKMB ›310, and DHL 3,469. During the hospital had pneumonia associated with Klebsiella pneumoniae for mechanical ventilation. We used meropenem for 7 days. 18 days after were extubated, without complications. The patient gradually recovered his renal function with decreased levels of muscle enzymes.

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