2015, Number 5
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ABSTRACTIntroduction: Angiostrongylus cantonensis is a helmint that lives in the pulmonary arteries of two rat’s species: Rattus rattus and Rattus norvergicus. Human is an accidental host that is infected by ingestion of third larvae stage in bad washed vegetables, fruit and different species of mollusks which constitute the intermitted hosts.
Objective: to characterize the humidity, temperature and rain fall in zones where were reported the patients and its relation with the eosinophilic meningoencephalitis cases by Angiostrongylus cantonensis.
Material and Methods: 34 patients were diagnosed with this illness. They were admitted at Hospital Pediatric San Miguel del Padrón, Havana, Cuba from January 1991 until January 2014. In order to obtain of meteorological variables data we remit to the admission patient date and dairy and monthly register of the Meteorology Institute. Were calculated the correlation coefficient for each meteorological variable and the number of cases related to the different variables and the regression lines were performed.
Results: the more quaintly of patients were grouped in periods where annual average fluctuated between 75 y 76 % and environment humidity oscillated between 65 y 80%.The probability to find illness cases is major in the years with average annual rain between 68 and more of 120mm. An inverse correlation was observed for temperature.
Conclusions: the larger number of reported cases coincides with the best conditions of environmental humidity and temperature for the development of the third stage larvae in mollusks.
Padilla-Docal B, Iglesias-González I, Bu-Coifiu-Fanego R, Socarrás Hernández CA, Dorta-Contreras AJ. Review: Intrathecal Activation as a Typical Immune Response within the Central Nervous System in Angiostrongyliasis. Am J Trop Med Hyg. 2013; 88(2): 230-235.
Li H, Feng X, Jin-Bao G, Xiao-Guang C. Case report: a severe eosinophilic meningoencephalitis caused by infection of Angiostrongylus cantonensis. Am J Trop Med Hyg. 2008; 79: 568-570.
Wang QP, Lai DH, Zhu XQ. Human angiostrongyliasis. Lancet Infect Dis. 2008; 8: 621-630.
Padilla-Docal B, Dorta-Contreras AJ. Different intrathecal immunoglobulins synthesis patterns in human host indicate different strains of Angiostrongylus cantonensis. Medical Hypotheses. 2012; 79:311-312.
Leone Sebastiano, De Marco Michele, Ghirga Piero, et al. Eosinophilic meningitis in a returned traveller from Santo Domingo: case report and review. J Travel Med. 2007; 14:407-10.
Raccurt C, Balaise J, Durette-Desset MC. Présenced´ Angiostrongylus cantonensis en Haití. Trop Med Intern Health. 2003; 8:423-6.
Graeff Texeira C. Expansion of Achatina fulica in Brazil and potential increased risk for angiostrongyliasis.Trans R Soc Trop Med Hyg. 2007; 8:743-4.
Pincay T, García L, Narváez E, et al. Angiostrongiliasis due to Parastrongylus (Angiostrongylus) cantonensis in Ecuador. First report in South America. Trop Med Internat Health. 2009; 14 (Suppl 2):37.
Padilla-Docal B, Dorta-Contreras AJ, Moreira Juan M, et al. Comparison of major immunoglobulins intrathecal synthesis patterns in Ecuadorian and Cuban patients with Angiostrongyliasis. Am J Trop Med Hyg. 2011; 84: 406-10.
Praphathip E, Phaik EL, Hongman Z, et al. Molecular differentiation andphylogenetic relationships of three Angiostrongylus species and Angiostrongylus cantonensis geographical isolates based on a 66-kDa protein gene of A. cantonensis (Nematoda: Angiostrongylidae). Exp Parasitol. 2010.
Himsworth CG, Parsons KL, Jardine C, Patrick DM. Rats, cities, people, and pathogens: A systematic review and narrative synthesis of literature regarding the ecology of rat-associated zoonoses in urban centers. Vector-Borne and Zoonotic Diseases. 2013; 13: 349-359.
Wang QP, Wu ZD, Wei J, Owen RL, Lun ZR. Human angiostrongylus cantonensis: An update. European Journal of Clinical Microbiology and Infectious Diseases. 2012; 31: 389-395.
Morton RF, Hebel J.R. Bioestadística y epidemiología. 3ª Ed., México: Interamericana; 1993.
Dorta-Contreras AJ, Padilla-Docal B, Moreira J. Neuroimmunological findings of Angiostrongylus cantonensis meningitis in Ecuadorian patients. Arq Neuropsiquiatr. 2011; 69: 466-499.
Morgan ER, Jefferies R, Krajewski M, Ward P, Shaw SE. Canine pulmonary angiostrongylosis: the influence of climate on parasite distribution. Parasitol Int. 2009; 58(4):406-10.
Foronda P, López-González M, Miquel J, Torres J, Segovia M, Abreu-Acosta N, et al. Finding of Parastrongylus cantonensis (Chen, 1935) in Rattus rattus in Tenerife, Canary Islands (Spain). Acta Trop. 2010; 114(2):123-7.
Tesana S, Srisawangwong T, Sithithaworn P, Laha T, Andrews R. Prevalence and intensity of infection with third stage larvae of Angiostrongylus cantonensis in mollusks from Northeast Thailand. Am J Trop Med Hyg. 2009; 80(6):983-7.
Meyer Willerer AO, Santos Soto A. temperature and light intensity affecting Egg production and growth performance of the apple snail Pomacea patula. Avances en Investigación Agropecuaria. 2006; 10: 41-58.
Zhang RL, Gao ST, Geng YJ, Huang DN, Chen MX, Liu JP, et al. Study on the epidemiological characteristics and natural infectious focus of Angiostrongylus cantonensis in Shenzhen area of Zhujiang Delta in China]. [Article in Chinese] Zhonghua Liu Xing Bing Xue Za Zhi. 2008; 29: 573-6.
Lv S, Zhou XN, Zhang Y, Liu HX, Zhu D, et al. The effect of temperature on the development of Angiostrongylus cantonensis (Chen 1935) in Pomacea canaliculata (Lamarck 1822). Parasitol Res. 2006; 99: 583-587.
Yousif F, Lämmler G. The effect of some biological and physical factors on infection of Biomphalaria glabrata with Angiostrongylus cantonensis. Parasitenk.1975; 47: 191-201.
Lv S, Zhang Y, Liu H-X, Hu L, Yang K, et al. Invasive Snails and an Emerging Infectious Disease: Results from the First National Survey on Angiostrongylus cantonensis in China. PLoS Negl Trop Dis. 2009; 3(2): e368.