Cueto-García J, Moreno MA, Bahena-Martínez Z, Rodríguez-Ayala E, Del Moral P, Ibáñez T, Moreno J

Language: Spanish
References: 13
Page: 102-108
PDF size: 393.86 Kb.

ABSTRACT

Chronic venous ulcerations remain a major challenge in medicine with incapacitating clinical and economic repercussions. Recent evidence indicates that as of 2015 there is not an effective treatment available superior to venous compression and simple dressings considered as the gold-standard. The maltodextrin polymer with zinc oxide is a biodegradable non-toxic type III Medical Device based on a natural vegetal polymer that in experimental and initial clinical evaluations has shown an improved healing of these ulcers with a marked improvement in the quality of life (control of pain, itching and secretions) and, due to its advantages of being cost-efficient, environmentally-friendly and not requiring refrigeration, it could represent an advantageous treatment for these chronic ulcerations.

REFERENCES

1. Thorne CHHM, Siebert JW, Grotting JC, Vasconez LO, Shaw W, Sauer PF. Úlceras vasculares. Reconstructive Surgery of the Lower Extremity. McCarthy JG, Plastic Surgery. WB Saunders; 1990, pp. 4076-79.

2. Gloviczki P, Comerota AJ, Dalsing MC, Eklof BG, Gillespie DL, Gloviczki ML, et al. The care of patients with varicose veins and associated chronic venous diseases: clinical practice guidelines of the Society for Vascular Surgery and the American Venous Forum. J Vasc Surg 2011; 53(5): 2S-48S.

3. Zenilman J, Valle MF, Malas MB, Maruthur N, Qazi U, Suh Y, et al. Chronic Venous Ulcers: A Comparative Effectiveness Review of Treatment Modalities. Rockville, MD Agency for Heathcare Research and Quality. 2013; 13(14): 1-77.127.

4. Margolis D, Berlin J, Strom B. Which venous leg ulcers will heal with limb compression bandages? Am J Med 2000; 109(1): 15-9.

5. Hodde JP, Allam R. Extracellular wound matrices: small intestinal Submucosa Wound Matrix for Chronic Wound Healing. Wounds 2007; 19(2): 157-62.

6. Nettel F, Rodríguez N, Nigro J, González M, Conde A, Muñoa A, et al. Primer consenso latinoamericano de úlceras venosas. Resumen. Rev Mex de Angiol 2013; 41(3): 95-126.

7. Kamolz LP, Wild T. Wound bed preparation: The impact of debridement and wound cleansing. Wound Medicine 2013; (1): 44-50.

8. Fife CE, Carter MJ, Walker D, Thomson B. Wound care outcomes and associated cost among patients treated in US outpatient wound centers: data from the US wound registry. Wounds: a compendium of clinical research and practice 2012; 24(1): 10-7.

9. Sen CK, Gordillo GM, Roy S, Kirsner R, Lambert L, Hunt T, et al. Human skin wounds: a major and snowballing threat to public health and the economy. Wound Repair and Regeneration 2009; 17(6): 763-71.

10. Moreno-Eutimio MA, Nieto-Velázquez NG, Espinosa- Monroy L, Torres-Ramos Y, Montoya-Estrada A, Cueto- García J, et al. Potent Anti-Inflammatory Activity of Carbohydrate Polymer with Oxide of Zinc. BioMed Research International 2014. Article ID 712312; 1-8: Disponible en: http://dx.doi.org/10.1155/2014/712312.

11. Cueto J, Barrientos T, Rodríguez E, Del Moral P. A new biodegradable adhesive for protection of intestinal anastomoses. Preliminary communication. Arch Med Research 2011; 42(6): 475-81.

12. Cueto J, Barrientos T, Rodríguez E, Espinosa L, Palma JC, Cojab J, et al. Further experimental studies on a biodegradable adhesive for protection of intestinal Anastomosis. Arch Med Research 2014; 45(4): 331-6.

13. Rice JB, Desai U, Cummings AK, Birnbaum HG, Skornicki M, Parsons N. Burden of venous leg ulcers in the United States. J Med Economics 2014; 17(5): 347-56.