2015, Number 4
Rev Mex Anest 2015; 38 (4)
Modification of the hemodynamic parameters and BIS during induction with propofol versus propofol-ketamine in pediatric patients
Alarcón-Almanza JM, Castro-Ortega J, Moyao-García D, Ramírez-Mora JC
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ABSTRACTThe anesthetic management is included in three phases: induction, maintenance and emersion. Intravenous drugs in inducing aim to maintain stability and hemostasis in the patients. The drugs most used for this purpose does not fully achieve this goal. The tendency to counteract these adverse effects of combining drugs with different action drugs. Material and methods: Blind randomized clinical trials study, which included patients from 1-10 years, ASA I-III elective surgery under general anesthesia. Two groups were formed. Propofol group (group p) 3 mg/kg of propofol was administered. Propofol ketamine group (group pk) propofol 2.5 mg/kg was administered and ketamine 0.5 mg/kg during induction. Baseline vital signs were recorded, at 1, 3 (endotracheal intubation), 5, 10 and 15 minutes. Results: 29 patients were included, 15 p group and 14 pk group. Both heart rate, blood pressure (systolic, diastolic and mean) and bispectral index decrease in the p group, not so in the pk group where vital signs were stable. Saturation did not change in any group. No statistically significant differences. Conclusions: The combination of propofol, ketamine compared with propofol as the only clinically inductor provides greater hemodynamic stability.