Yáñez-Gutiérrez L, López-Gallegos D, Cerrud-Sánchez CE, Márquez-González H, García-Pacheco MB, Jiménez-Santos M, Santiago-Hernández JA, Ramírez-Reyes HA, Riera-Kinkel C

Language: English
References: 10
Page: 195-200
PDF size: 1351.24 Kb.

ABSTRACT

Objective: To describe conduct, evolution and surgical treatment of ALCAPA in adult patients. Material and methods: Series of five cases, › eighteen years old. Clinical data (including surgery and follow-up), and echocardiographic/hemodynamic studies were reviewed. Results: The series comprised four women (80%) and a man (20%), with a mean age of 38.2 (range 18-65) years. Myocardial ischemia was found in three patients (60%), detection of a cardiac murmur in one patient (20%) and aborted sudden death in one patient (20%). Physical examination was normal in every case. Two patients (40%) presented grade II cardiomegaly and venocapillary pulmonary hypertension. In three cases, subendocardial ischemia was found on the EKG without necrosis evidence. Echocardiogram was performed in every patient. On the short axis window turbulent (mosaic) retrograde flow on left interventricular septum and left coronary artery absence was documented. Myocardial scintigraphy was performed on four patients finding moderate to severe anterolateral ischemia. CT angiography was performed on 80% of cases. In 40% of patients, left ventricular end diastolic pressure was elevated in cardiac catheterization. Surgical repair was successful in every case. Coronary reimplantation was performed on two patients, Takeuchi procedure was performed on two patients and revascularization with an internal mammary artery-to-anomalous left coronary artery from the pulmonary artery procedure in one patient. After 48 months of follow-up, every patient is alive in functional class I. Conclusions: Natural history of ALCAPA includes chronic ischemia, ventricular dysfunction and severe arrhythmias that could lead to death. There are very few cases in adults and the likelihood of reaching this age depends on collateral circulation provided by the right coronary artery. This was found in each case in this series, documented by echocardiography and cardiac catheterization. Surgical procedures for this entity include coronary reimplantation, Takeuchi procedure and internal mammary artery-to-anomalous left coronary artery from the pulmonary artery procedure (performed in one patient on this series). Prognosis is good, as long as the congenital defect is corrected.

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