Jiménez SJ, Díaz ÁHR, Veliz SMI

Language: Spanish
References: 8
Page: 13-18
PDF size: 253.16 Kb.

ABSTRACT

Chronic Obstructive Pulmonary Disease (COPD) frequently has secondary exacerbations produced by respiratory infections. It can complicate with multiple organ failure and including endothelial dysfunction syndrome characterized by vasoconstriction or vasodilatation; capillary permeability increase, intestinal bacterium translocation, renal protein lose, intravascular coagulation and hyperglycemic. A 54 year-woman is presented with previous chronic obstructive pulmonary disease, she was admitted with dyspnea and a lung infection was diagnosed, needing tracheotomy and mechanical ventilation. Evolutionally she presented widespread edemas with pericardial and pleural effusion and peritoneal fluid collection, multiple organ failure with affection of respiratory, digestive, cardiovascular and renal systems as well as hyperglycemic and electrolyte and water body disturbance with mixed acidosis were diagnosed. The microalbuminuria showed more that 200 ng/dl. It was interpreted as an endothelial dysfunction syndrome. In conclusion, the endothelial system should be considered as a vital organ and take into account its failure as a part of the multiple organs dysfunction syndrome.

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