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2015, Number 4

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Dermatología Cosmética, Médica y Quirúrgica 2015; 13 (4)

Blue man syndrome associated to retigabine drug: a case report

Pérez-Lizárraga RI, Hernández-Collazo AA, Hernández-Arana MS
Full text How to cite this article

Language: Spanish
References: 14
Page: 331-334
PDF size: 148.29 Kb.


Key words:

retigabine, ezoganine, blue man syndrome, drug induced dyschromia.

ABSTRACT

Previously known as blue man syndrome, to the diffuse bluegray dyschromia caused by chronic silver exposure. Currently, there are other entities that cause this syndrome, like some drugs. Recently reported adverse event of retigabine (ezogabine), characterized by changes in pigmentation of skin, nails and retina, also known as blue man syndrome. Despite that the mechanism of these pigment changes have not been determined, it is well known the potential reversibility of the dyschromia. The Food and Drug Administration of the United States (fda) has issued an alert, forcing to place a label informing about the risk for retinal and skin pigmentation.


REFERENCES

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Dermatología Cosmética, Médica y Quirúrgica. 2015;13