2015, Number 259
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ABSTRACTDuring a lot of time, the structural and functional importance of the primary cilium was discarded. The technological advance to beginnings of the present century it has propitiated the understanding of their relevance. Due to their cellular wide distribution, their emergent paper in the transduction of important signaling roads and their dysfunctions, it has been implied in a wide spectrum of human illnesses denominated cilium sicks, in which are common discoveries the neurological defects. To recognize how the genes associated to the ciliums are involved in diverse neurological syndromes it has improved the understanding of the functions of the primary cilium in Nervous Central System (NCS). In accordance with what one comes saying, after the revision of 61 bibliographical references, this analysis seeks to describe the molecular relationship and morfofuncional of the cilium sicks in the organism. The knowledge of the primary cilium and of the acting that has been attributed, it will allow the elucidation of an important number of genetic illnesses associated to their dysfunction.
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