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2016, Number 1

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Rev Clin Esc Med 2016; 6 (1)

Sindrome de Brugada

Pacheco OE, Grant VS

Language: Spanish
References: 15
Page: 117-120
PDF size: 777.71 Kb.


ABSTRACT

The Brugada Síndrome is one of the most important causes of sudden cardiac arrest and sudden cardiac death, due to ventricular fibrillation. It belongs to a serie of rhythm abnormalities where no cardiac structure damage is detected. The variable genetic penetration of the syndrome causes that many patients can be asymptomatic whereas others can perish before the first year of living. The mutation of a sodium channel is the direct cause and the mutation of the SCN5A gene is directly related to this abnormalities and there are other gene mutations that are currently under study. Medications are not actually the first line of treatment for symptomatic patients, currently the ICP (implantable cardioverter- defibrillator) should be the first line therapy for nearly all patients.


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