Sánchez-Zamora R, Vera-Gaspar D, Álvarez-Goris MP, Rojas-Sánchez TMR, Peña-Jiménez AE

Language: Spanish
References: 10
Page: 65-71
PDF size: 512.63 Kb.

ABSTRACT

Objective: This study was conducted to compare the correlation between the Pap smear and colposcopy findings in postmenopausal Mexican women.
Material and Method: Observational, Retroelective, longitudinal, descriptive study, all menopausal women who consulted for pap smears and colposcopy performed was studied.
Results: 119 patients were evaluated. 72 % of pap smears were negative to human papilloma virus, 29 (24 %) had a low-grade lesion and 4 (4%) had a high-grade lesions. In the colposcopic study: 31 studies (26%) report low-grade intraepithelial lesion and 2 cases (2%) high-grade lesion. The histopathological biopsy reported one invasive cervical cancer ( 2.43 %) and 20 cases of low-grade lesions ( 48.7 %). cytology had a sensitivity of 85.3 % and specificity of 56.09 % with a false negative rate of 14.3 %, a positive predictive value of 66.03 % and a negative predictive value of 79.31 %. Colposcopy: sensitivity= 82.92 %, specificity = 56.09 % with a false negative rate of 17.07 % positive predictive value of 65.38 % and a negative predictive value of 76.66 %.
Conclusions: The correlation between Pap smear and colposcopy shows that the diagnosis of low and high grade lesions differs only by 2%, therefore indicates adequate sensitivity for diagnosis. In this population of women routine gynecological tests most be performed

REFERENCES

1. Ko EM, Tambouret R, Wilbur D, Goodman AHPV. Reflex Testing in Menopausal Women. Patholog Res Int. 2011 Apr 7;2011:181870.

2. Jemal A, Bray F, Center MM, Ferlay J, Ward E, Forman D. Global cancer statistics. CA Cancer J Clin.2011; 61(2): 69-90.

3. La Cruz Pelea C, Fariña González J. Citología ginecológica: de Papanicolaou a Bethesda, Editorial Complutense, 2003: 24.

4. Gilani SM, Mazzara PF Cytohistologic correlation in premenopausal and postmenopausal women. Acta Cytol. 2013;57(6):575-580.

5. Rositch AF, Silver MI, Burke A, Viscidi R, Chang K, Duke CM, et al. The correlation between human papillomavirus positivity and abnormal cervical cytology result differs by age among perimenopausal women. J Low Genit Tract Dis. 2013 Jan;17(1):38-47.

6. Freeman-Wang T, Walker P. Colposcopy in special circumstances: Pregnancy, immunocompromise, including HIV and transplants, adolescence and menopause. Best Pract Res Clin Obstet Gynaecol. 2011 Oct;25(5):653-65.

7. Frank JE. The colposcopic examination. J Midwifery Womens Health. 2008 Sep-Oct;53(5):447-452.

8. Ortega González C. Tópicos selectos en endocrinología reproductiva. México: Alfil, 2010.

9. Lindau ST, Drum ML, Gaumer E, Surawska H, Jordan JA Prevalence of high-risk human papillomavirus among older women. Obstet Gynecol. 2008 Nov;112(5):979- 989.

10. Llanos VA, Vera GD. Control de calidad en citología, colposcopia y estudios anatomopatológicos. AMATGI 2012; 3(6): 10-15.