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2016, Number 2

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Rev Cubana Invest Bioméd 2016; 35 (2)

Biomechanical analysis of the optic disc under variations in intraocular pressure and scleral rigidity

Calderín PB, González CRA, Landín SM, Nápoles PE

Language: Spanish
References: 22
Page: 147-157
PDF size: 261.66 Kb.


ABSTRACT

Introduction: Increase in intraocular pressure and alterations in the appearance of the optic nerve head are important factors in determining the progress of glaucomatous damage.
Objective: Analyze the behavior of the optic disc under the effect of variations in intraocular pressure and scleral rigidity using a biomechanical model.
Methods: The finite element method was used to define several rigidity modules for the sclera at 3.6 and 9 MPa and for the lamina cribosa at 0.3 and 0.6 MPa. All the tissues modeled were assumed to be isotropic materials with elastic, incompressible behavior.
Results: The highest concentration of tensions was located in areas of the peripapillary sclera and scleral canal walls. Tension and displacement peaks (97.523 kPa and 95.64 µm, respectively) were obtained when the sclera and the lamina cribosa were less rigid and intraocular pressure was highest.
Conclusions: The biomechanical characteristics of the optic disc influence the development of glaucomatous optic neuropathy. The greatest displacement is found in the central area of the optic disc, and it is associated with the loss of retinal nerve fibers or an increase in papillary excavation in the mechanism of glaucomatous damage.


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